Bio-inspired Electrospun Fibre Structures - Numerical Model (CROSBI ID 202065)
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Podaci o odgovornosti
Mijović, Budimir ; Agić, Ante
engleski
Bio-inspired Electrospun Fibre Structures - Numerical Model
A systems approach that integrates processing, structure, property and performance relations has been used in the design of multilevel-structured fibrous materials. For electrospun fibrous structure, numerical implementation of multiscale materials philosophy provides a hierarchy of computational models defining design parameters that are integrated through computational continuum mechanics. Electrospun micro/nano (multiscale) poly("-caprolactone) (PCL) fibrous scaffolds were studied. The fibrous structures were evaluated for their mechanical, morphological and cell attachment properties. The cell attachment studies showed that cell activity on multi-scale scaffolds was higher compared to micro-fibrous scaffolds. These results suggest that the combination of a micro- and nano-fiber hierarchical sca?old could be more beneficial for tissue engineering applications than for individual scaffolds.
Electrospun PCL; Multiscale; Numerical Model
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