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Pregled bibliografske jedinice broj: 676228

Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma


Košec, Andro; Svetina, Lucija; Lukšić, Ivica
Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma // International journal of oral and maxillofacial surgery, 42 (2013), 1; 82-88 doi:10.1016/j.ijom.2012.10.007 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 676228 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma

Autori
Košec, Andro ; Svetina, Lucija ; Lukšić, Ivica

Izvornik
International journal of oral and maxillofacial surgery (0901-5027) 42 (2013), 1; 82-88

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
head and neck cutaneous squamous cell carcinoma; neck dissection; regional metastasis; parotid region; clinical staging

Sažetak
The authors analyzed a new clinical staging system and its correlation with pathologic findings and patient survival. Patients were eligible for inclusion in this longitudinal retrospective cohort study if they had cutaneous squamous cell carcinoma on the head or neck, underwent surgery and had a minimum 3 year follow-up. The primary study variable was using a new clinical staging system. Secondary variables included the parotid as a predictor of metastatic spread to the lymphatic nodes in the neck and primary lesion histopathologic traits. The outcome variable was patient survival. Associations between variables were assessed using Fisher’s exact test, Mann-Whitney test, Kaplan-Meier method and Mantel log-rank test. P<0.05 was considered significant. The sample was composed of 103 patients. Regional metastatic disease was found in 24 patients. Histopathological analysis showed a higher frequency of neck metastatic disease if the parotid was positive for metastases (p=0.022). An extended staging system showed significant correlation between survival rate and substages (p=0.0105). Perineural invasion was a negative prognostic factor (p=0.0151) The results of this study suggest that combining curative parotidectomy and elective neck dissection could be beneficial in high risk patients. Both neck and parotid metastases should be included in the clinical and histological N classification.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-1080057-0043 - Nacionalni model kliničke baze podataka u maksilofacijalnoj onkologiji (Virag, Mihajlo, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice",
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb

Profili:

Avatar Url Ivica Lukšić (autor)

Citiraj ovu publikaciju

Košec, Andro; Svetina, Lucija; Lukšić, Ivica
Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma // International journal of oral and maxillofacial surgery, 42 (2013), 1; 82-88 doi:10.1016/j.ijom.2012.10.007 (međunarodna recenzija, članak, znanstveni)
Košec, A., Svetina, L. & Lukšić, I. (2013) Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma. International journal of oral and maxillofacial surgery, 42 (1), 82-88 doi:10.1016/j.ijom.2012.10.007.
@article{article, year = {2013}, pages = {82-88}, DOI = {10.1016/j.ijom.2012.10.007}, keywords = {head and neck cutaneous squamous cell carcinoma, neck dissection, regional metastasis, parotid region, clinical staging}, journal = {International journal of oral and maxillofacial surgery}, doi = {10.1016/j.ijom.2012.10.007}, volume = {42}, number = {1}, issn = {0901-5027}, title = {Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma}, keyword = {head and neck cutaneous squamous cell carcinoma, neck dissection, regional metastasis, parotid region, clinical staging} }
@article{article, year = {2013}, pages = {82-88}, DOI = {10.1016/j.ijom.2012.10.007}, keywords = {head and neck cutaneous squamous cell carcinoma, neck dissection, regional metastasis, parotid region, clinical staging}, journal = {International journal of oral and maxillofacial surgery}, doi = {10.1016/j.ijom.2012.10.007}, volume = {42}, number = {1}, issn = {0901-5027}, title = {Significance of clinical stage, extent of surgery and outcome in cutaneous head and neck squamous cell carcinoma}, keyword = {head and neck cutaneous squamous cell carcinoma, neck dissection, regional metastasis, parotid region, clinical staging} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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