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Pregled bibliografske jedinice broj: 676009

Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study


Burisch, J; Pedersen, N; Čuković-Čavka, Silvija; Turk, Nikša; ...; Munkholm, P.
Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study // Journal of Crohn's and colitis, 8 (2014), 7; 607-616 doi:10.1016/j.crohns.2013.11.021 (međunarodna recenzija, članak, znanstveni)


Naslov
Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe - An ECCO-EpiCom study

Autori
Burisch, J ; Pedersen, N ; Čuković-Čavka, Silvija ; Turk, Nikša ; ... ; Munkholm, P.

Izvornik
Journal of Crohn's and colitis (1873-9946) 8 (2014), 7; 607-616

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Inflammatory bowel disease (IBD); environmental factors; population-based inception cohort

Sažetak
The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe possibly due to changes in environmental factors towards a more "westernised" standard of living. The aim of this study was to investigate differences in exposure to environmental factors prior to diagnosis in Eastern and Western European IBD patients. The EpiCom cohort is a population-based, prospective inception cohort of 1560 unselected IBD patients from 31 European countries covering a background population of 10.1million. At the time of diagnosis patients were asked to complete an 87-item questionnaire concerning environmental factors. A total of 1182 patients (76%) answered the questionnaire, 444 (38%) had Crohn's disease (CD), 627 (53%) ulcerative colitis (UC), and 111 (9%) IBD unclassified. No geographic differences regarding smoking status, caffeine intake, use of oral contraceptives, or number of first-degree relatives with IBD were found. Sugar intake was higher in CD and UC patients from Eastern Europe than in Western Europe while fibre intake was lower (p<0.01). Daily consumption of fast food as well as appendectomy before the age of 20 was more frequent in Eastern European than in Western European UC patients (p<0.01). Eastern European CD and UC patients had received more vaccinations and experienced fewer childhood infections than Western European patients (p<0.01). In this European population-based inception cohort of unselected IBD patients, Eastern and Western European patients differed in environmental factors prior to diagnosis. Eastern European patients exhibited higher occurrences of suspected risk factors for IBD included in the Western lifestyle.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

Napomena
The EpiCom-group.



POVEZANOST RADA


Projekt / tema
108-1081874-1917 - Upalne bolesti crijeva (Crohnova bolest i ulcerozni kolitis) (Boris Vucelić, )

Ustanove
Medicinski fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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