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Pregled bibliografske jedinice broj: 675532

Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents


Radošević, Kristina; Cvjetko Bubalo, Marina; Gaurina Srček, Višnja; Grgas, Dijana; Landeka Dragičević, Tibela; Radojčić Redovniković, Ivana
Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents // Ecotoxicology and environmental safety, 112 (2015), 46-53 doi:10.1016/j.ecoenv.2014.09.034 (međunarodna recenzija, članak, znanstveni)


Naslov
Evaluation of toxicity and biodegradability of choline chloride based deep eutectic solvents

Autori
Radošević, Kristina ; Cvjetko Bubalo, Marina ; Gaurina Srček, Višnja ; Grgas, Dijana ; Landeka Dragičević, Tibela ; Radojčić Redovniković, Ivana

Izvornik
Ecotoxicology and environmental safety (0147-6513) 112 (2015); 46-53

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Deep eutectic solvents; in vitro toxicity; phytotoxicity; biodegradability; choline chloride

Sažetak
Deep eutectic solvents (DESs) have been dramatically expanding in popularity as a new generation of environmentally friendly solvents with possible applications in various industrial fields, but their ecological footprint has not yet been thoroughly investigated. In the present study, three choline chloride-based DESs with glucose, glycerol and oxalic acid as hydrogen bond donors were evaluated for: in vitro toxicity using fish and human cell line, phytotoxicity using wheat and biodegradability using wastewater microorganisms through closed bottle test. Obtained in vitro toxicity data on cell lines indicate that choline chloride:glucose and choline chloride:glycerol possess low cytotoxicity (EC50>10 mM for both cell lines) while choline chloride:oxalic acid possess moderate cytotoxicity (EC50 value 1.64 mM and 4.19 mM for fish and human cell line, respectively). Results on phytotoxicity imply that tested DESs are non-toxic with seed germination EC50 values higher than 5 000 mg L- 1. All tested DESs were classified as ‘readily biodegradable’ based on their high levels of mineralization (68-96%). These findings indicate that DESs have a green profile and a good prospect for a wider use in the field of green technologies.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija



POVEZANOST RADA


Projekt / tema
058-0582184-2414 - Nekliničke metode ispitivanja tvari iz okoliša na stanicama sisavaca i riba (Višnja Gaurina-Srček, )
058-0582261-2256 - Biološki aktivni spojevi domaćih sorta brokule i kakao zrna. (Ivana Radojčić Redovniković, )
058-0583444-3494 - Uloga biopolimera kao čimbenika postojanosti granule mješovite mikrobne kulture (Tibela Landeka Dragičević, )

Ustanove
Prehrambeno-biotehnološki fakultet, Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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