engleski

Global cardiovascular risk in newly diagnosed hypertension and prehypertension

AIM:To analyze the prevalence and cardiovascular risk factors of individuals with normal blood pressure (BP) and those with untreated hypertension in a cohort of subjects enrolled in an epidemiological survey performed in the continental rural part of Croatia. METHODS:Out of 1375 subjects enrolled in the survey, 495 (216 men and 279 women) were included into study. Exclusion criteria were: treated hypertension, acute illness, chronic terminal disease, pregnancy, usage of nonsteroid anti- inflammatory drugs or corticosteroids therapy, dementia and immobility. BP was measured three times in a sitting position using the OMRON device. Subjects were classified into groups with optimal BP (<120/80 mmHg), prehypertension (120/80-140/90 mmHg) and hypertension (>140/90mmHg). Height, weight, body mass index and waist circumference were determined. Fasting blood was analyzed for glucose (FBG) and lipid status. RESULTS: Optimal BP had 131 (26.4%), prehypertension 174 (35.2 %) and untreated hypertension 190 (38.4%) of enrolled persons. From 190 hypertensives, 19 were priory diagnosed but untreated, while the rest were newly diagnosed. Significant differences were observed in age, BMI, waist circumference, total and LDL cholesterol, FBG, triglycerides (p<0, 001) between newly diagnosed hypertensives and other two groups. Prehypertensives and subjects with optimal BP significantely differed in all parameters (p<0.001) beside FBG and triglycerides. There were no significant differences in HDL cholesterol values among groups (p=0.363). CONCLUSION: Significant differences were observed in age, BMI, waist circumference, total and LDL cholesterol, FBG, triglycerides (p<0, 001) between newly diagnosed hypertensives and other two groups. Prehypertensives and subjects with optimal BP significantely differed in all parameters (p<0.001) beside FBG and triglycerides. There were no significant differences in HDL cholesterol values among groups (p=0.363).

cardiovascular risk ; hypertension ; prehypertension

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