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Pregled bibliografske jedinice broj: 671675

Two rare cases of central nervous system opportunistic mycoses

Mlinarić Missoni, Emilija; Baršić Bruno
Two rare cases of central nervous system opportunistic mycoses // Arhiv za higijenu rada i toksikologiju, 63 (2012), 4; 505-511 doi:10.2478/10004-1254-63-2012-2241 (međunarodna recenzija, članak, znanstveni)

Two rare cases of central nervous system opportunistic mycoses

Mlinarić Missoni, Emilija ; Baršić Bruno

Arhiv za higijenu rada i toksikologiju (0004-1254) 63 (2012), 4; 505-511

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Central nervous system ; oprotunistic mycosis

This article presents two cases of opportunistic mycoses (OMs) of the central nervous system (CNS) caused by Cryptococcus neoformans and Aspergillus nidulans, respectively. The patients were hospitalised in local hospitals between 2009 and 2011 because of unspecific symptoms (fever, headache, and/or weight lost). Duration of symptoms varied from 4 days to over 2 weeks. The patients were treated with antibiotics and symptomatically. OM was not suspected in any of them. The patients became critically ill with symptoms of CNS involvement and were transferred to the Intensive Care Unit (ICU) of the University Hospital for Infectious diseases (UHID) in Zagreb. None of the patients belonged to the high-risk population for developing OMs. They were not HIV-infected, had no transplantation of bone marrow or solid organ, and were not on severe immunosuppressive chemotherapy. Fungi were isolated from cerebrospinal fluid (CSF) samples and, in one patient, from aspirate of cerebral abscess. Isolation and mycological identification of all fungal isolates and in vitro antifungal susceptibility testing of these isolates were done at the Reference Centre for Mycological Diagnostics of Systemic and Disseminated Infections (RCMDSDI) in Zagreb. The patient with cryptococcal meningitis was treated with amphotericin B and fluconazole and the patient with cerebral aspergilloma with voriconazole.

Izvorni jezik


Projekt / tema
108-1080002-0102 - Procjena potrebe i učinkovitosti liječenja teških infekcija u JIM (Bruno Baršić, )
108-1080114-0017 - Genotipovi i činitelji virulencije uzročnika bolničkih infekcija (Ana Budimir, )

Medicinski fakultet, Zagreb

Časopis indeksira:

  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus