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Pregled bibliografske jedinice broj: 669824

Preovulatory progesterone rise during ovarian stimulation for IVF


Kasum, Miro; Radaković, Branko; Šimunić, Velimir; Orešković, Slavko
Preovulatory progesterone rise during ovarian stimulation for IVF // Gynecological endocrinology, 29 (2013), 8; 744-748 doi:10.3109/09513590.2013.798280 (međunarodna recenzija, članak, znanstveni)


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Naslov
Preovulatory progesterone rise during ovarian stimulation for IVF

Autori
Kasum, Miro ; Radaković, Branko ; Šimunić, Velimir ; Orešković, Slavko

Izvornik
Gynecological endocrinology (0951-3590) 29 (2013), 8; 744-748

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
progesterone; IVF; ovulation

Sažetak
The aim of this review is to analyze the relationship between the preovulatory progesterone (P) rise and the in vitro fertilization (IVF) pregnancy outcome. It also investigates the sources and effects of P level increase, including the underlying mechanisms and potential strategies in preventing its elevation during ovarian stimulation. The origin of production of P in the early follicular phase is adrenal which shifts toward the ovaries prior to the ovulation. Several factors contribute to the etiology of P level increase including the number of multiple follicles, the overdose of gonadotropins and poor ovarian response. Nowadays, the influence of the preovulatory P rise on IVF outcome remains controversial. Several authors have failed to demonstrate any negative impact, while others reported a detrimental effect associated with the rise of P. It seems that P rise (≤ 1.5 ng/ml or 4.77 nmol/l) may have deleterious effects on endometrial receptivity, namely, accelerating the endometrial maturation process that subsequently narrows the time-frame for implantation and thus decreases pregnancy rates. To prevent a P rise, it might be preferable to use milder stimulation protocols, earlier trigger of ovulation, cryopreservation of all embryos and transfer in the natural cycle.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-0000000-0388 - Etiologija i patogeneza PCOS - odabir terapije i metaboličke posljedice (Pavičić Baldani, Dinka, MZOS ) ( POIROT)
108-1080399-0383 - Muški i ženski spolni sustav: razvoj, normalna histofiziologija i neplodnost (Ježek, Davor, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Citiraj ovu publikaciju

Kasum, Miro; Radaković, Branko; Šimunić, Velimir; Orešković, Slavko
Preovulatory progesterone rise during ovarian stimulation for IVF // Gynecological endocrinology, 29 (2013), 8; 744-748 doi:10.3109/09513590.2013.798280 (međunarodna recenzija, članak, znanstveni)
Kasum, M., Radaković, B., Šimunić, V. & Orešković, S. (2013) Preovulatory progesterone rise during ovarian stimulation for IVF. Gynecological endocrinology, 29 (8), 744-748 doi:10.3109/09513590.2013.798280.
@article{article, year = {2013}, pages = {744-748}, DOI = {10.3109/09513590.2013.798280}, keywords = {progesterone, IVF, ovulation}, journal = {Gynecological endocrinology}, doi = {10.3109/09513590.2013.798280}, volume = {29}, number = {8}, issn = {0951-3590}, title = {Preovulatory progesterone rise during ovarian stimulation for IVF}, keyword = {progesterone, IVF, ovulation} }
@article{article, year = {2013}, pages = {744-748}, DOI = {10.3109/09513590.2013.798280}, keywords = {progesterone, IVF, ovulation}, journal = {Gynecological endocrinology}, doi = {10.3109/09513590.2013.798280}, volume = {29}, number = {8}, issn = {0951-3590}, title = {Preovulatory progesterone rise during ovarian stimulation for IVF}, keyword = {progesterone, IVF, ovulation} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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