Naslov
Physico-Chemical Mehtods in Drug Discovery and Development

Autori
Mandić, Zoran

Vrsta, podvrsta i kategorija knjige
Autorske knjige, monografija, znanstvena

Izdavač
IAPC Publishing

Grad
Zagreb

Godina
2012

Stranica
482

ISBN
978-953-56942-0-5

Ključne riječi
Physico-chemical profiling; permeability; lipophilicity; protein-ligand interactions; thermal analysis; polymorphism; chiral separations; NIR; NMR; chromatography; HPLC;

Sažetak
Physical chemistry underlies most of the tools that medicinal chemists have at hand to assist them in their research. The vast armada of physico-chemical methods and techniques available enable fast and accurate measurements of specific parameters facilitating identification and selection of drug candidates. However, appropriate applications of physico-chemical techniques or their combinations, the proper choice of the corresponding methods as well as accurate interpretation of the results relies not only on good knowledge of physical chemistry but also on open and active communication between scientists of various backgrounds. This book gives a selection of topics related to the various methods commonly used in pharmaceutical research. The intention, on the one hand, is to provide a theoretical background of the particular technique in order to enable inexperienced readers to gain a general impression of the usefulness of the field. On the other hand, a lot of practical examples will provide scientists, who encounter these methods either in the pharmaceutical research process or in academic institutions, with enough useful information for the successful application of these methods in their everyday work.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Temeljne tehničke znanosti

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