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Pregled bibliografske jedinice broj: 655633

Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs


Novak, Igor; Klasinc, Leo; Chong, Delanopun; McGlynn, Séan P.
Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs // Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 112 (2013), 110-115 doi:10.1016/j.saa.2013.04.012 (međunarodna recenzija, članak, znanstveni)


Naslov
Photoelectron spectroscopy of non-steroidal anti-inflammatory drugs

Autori
Novak, Igor ; Klasinc, Leo ; Chong, Delanopun ; McGlynn, Séan P.

Izvornik
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (1386-1425) 112 (2013); 110-115

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Biological activity ; non-steroidal anti-inflammatory drugs ; photoelectron spectroscopy

Sažetak
The electronic structures of eight non-steroidal anti-inflammatory drugs (NSAIDs) had been studied by UV photoelectron spectroscopy (UPS) and high-level Green's function (GF) calculations. Our UPS data show that the electronic structure influences the measured biological activity of NSAID, but that it is not the dominating factor. The role of electronic structure needs to be considered in conjunction with other factors like steric properties of the COX active site and orientation of relevant residues in the same site

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
098-0982915-2945 - Spektroskopija, kemijska svojstva i reakcije biološki aktivnih molekula (Branka Kovač, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Leo Klasinc, (21130)
Igor Novak, (74291)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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