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Pregled bibliografske jedinice broj: 650801

The effect of Amaranth oil on monolayers of artificial lipids and hepatocyte plasma membranes with adrenalin-induced stress


Yelisyeyeva, O.P.; Semen, K.O.; Ostrovska, G.V.; Kaminskyy, D.V.; Sirota, T.V.; Žarković, Neven; Mazur, D.; Lutsyk, O.D.; Rybalchenko, K.; Bast, A.
The effect of Amaranth oil on monolayers of artificial lipids and hepatocyte plasma membranes with adrenalin-induced stress // Food chemistry, 147 (2013), 152-159 doi:10.1016/j.foodchem.2013.09.119 (međunarodna recenzija, članak, znanstveni)


Naslov
The effect of Amaranth oil on monolayers of artificial lipids and hepatocyte plasma membranes with adrenalin-induced stress

Autori
Yelisyeyeva, O.P. ; Semen, K.O. ; Ostrovska, G.V. ; Kaminskyy, D.V. ; Sirota, T.V. ; Žarković, Neven ; Mazur, D. ; Lutsyk, O.D. ; Rybalchenko, K. ; Bast, A.

Izvornik
Food chemistry (0308-8146) 147 (2013); 152-159

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Adaptive stress response; adrenalin-induced stress; amaranth oil; hormetic response; membrane monolayer; neurotensin; oxidative stress correction; rats

Sažetak
In this paper the oil from seeds of Amaranthus cruentus L. (AmO) was shown to be an efficient modulator of the physical chemical properties of artificial lipid and rat hepatocyte plasma membranes. AmO improved the membrane stability, their stress resistance and the adsorption of neurotensin to plasma membranes with the distinct biphasic interactions being observed even after adrenalin stress exposure. The analysis of pro-/antioxidant balance in rat blood revealed a mild prooxidant activity after AmO intake, which was accompanied by accumulation of oxidative destruction products in plasma membranes. This prooxidant action of AmO was corroborated in vitro in an adrenalin autooxidation model. On the other hand, the observed improved resistance to adrenalin stress in AmO supplemented rats was associated with an antioxidant response in blood and plasma membrane studies. The AmO effects can be attributed to the modulation of the metabolic pathways involved into oxygen and free radical homeostasis.

Izvorni jezik
Engleski



POVEZANOST RADA


Projekt / tema
098-0982464-2519 - Lipidi, slobodni radikali i njihovi glasnici u integrativnoj onkologiji (Neven Žarković, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Neven Žarković, (126952)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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