engleski

Blood pressure variabillity in normotensive patients-correlation to body mass index and age

The aim of the study was to show the differences in BPV regarding gender, age and body mass index (BMI) in normotensive patients. The study included 40 normotensive patients (22 women and 18 men. Ambulatory blood pressure monitoring (ABPM) was performed using Spacelab 90217 monitor. From these measurements we obtained data on overall (o), wake (w) and sleep (s) systolic (SBP) and diastolic (DBP) blood pressure, mean arterial pressure (MAP) heart rate (HR) and percentage of time when SBP, DBP and MAP were above limits (%TAL). Patients were divided into groups regarding gender, BMI < or > 25 kg/m2 and age < or > 40. Three ABPMs were not technically acceptable, and three cases of hypertension were detected (2 men and 1 woman). Thirty-four ABPMs were statistically analyzed (21 female, 13 male). There were no significant differences in age or BMI between men and women or within groups. oSBP (p = 0.028), oPP and oPP variability (p = 0.023, p = 0.005, respectively), o%TAL of SBP (p = 0.048), wSBP and BPV of wSBP (p = 0.031 and p = 0.005, respectively) were significantly higher in group of patients with BMI > 25 kg/m2. BPV of wDBP correlated to BMI in women (p = 0.008). Men had significantly higher oSBP compared to women (p = 0.029) as well as BPV of oSBP (p = 0.01). They had significantly greater o%TAL of SBP (p = 0.02) and o%TAL of DBP (p = 0.018) as well as wSBP (p = 0.02). oSBP and o%TAL of SBP correlated to BMI in women (p = 0.012, p = 0.02, respectively), but not in men. Both absolute blood pressure values and BPV of systolic blood pressure during the daytime correlated with BMI in all patients. This study showed connection between BPV of diastolic blood pressure during the nighttime and BMI of female patients. No difference in BPV was detected regarding the age of patients. Men have higher SBP and BPV of SBP then women during the 24 hour period as well as longer period of time with values above limits.

systolic blood pressure; diastolic blood pressure; body mass index; age; obesity

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