Naslov
Effect of perinatal treatment with serotonin agonists on immunological and hematological parameters in adult rats

Autori
Lipovec, Valentina ; Horvat Knežević, Anica ; Erhardt, Julija ; Blažević, Sofia Ana ; Hranilović, Dubravka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts 4th Croatian Congress of Neuroscience / / - Zagreb : Croatian Society for Neuroscience, Croatian Insitute for Brain Research, 2013, 48-48

Skup
4th Croatian Congress of Neuroscience

Mjesto i datum
Zagreb, Hrvatska, 20.09.2013. - 21.09.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
serotonin ; 5-hydroxytryptophan ; tranylcipromine ; blood cells ; lymphatic tissue ; cytokines

Sažetak
Serotonin (5HT) is a biogenic amine present in the central nervous system and peripheral tissues, including the components of the immune system. Consequences of disrupted homeostasis of serotonin were observed in hematological and immunological parameters in adult rats. Treatment had an effect on the blood cells - males TCP treated group had increased total leukocyte count, and a group of males treated with 5HTP and TCP had significantly reduced the number of platelets. Treatment had an impact on immunological parameters (concentration of cytokines). 5HTP treated group had elevated levels of IL1-a, and the group treated with TCP had reduced level of IL1-a.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA