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The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease (CROSBI ID 196023)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Karabuva, Svjetlana ; Carević, Vedran ; Radić, Mislav ; Fabijanić, Damir The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease // Biochemia medica, 23 (2013), 3; 351-359

Podaci o odgovornosti

Karabuva, Svjetlana ; Carević, Vedran ; Radić, Mislav ; Fabijanić, Damir

engleski

The association of ABO blood groups with extent of coronary atherosclerosis in Croatian patients suffering from chronic coronary artery disease

AIM of study was to: 1) examine the relationship between ABO blood groups and extent of coronary atherosclerosis in patients with chronic coronary artery disease (CAD), 2) compare ABO blood groups distribution in CAD patients and general population, 3) examine possible differences in traditional risk factors frequency in CAD patients with different ABO blood groups. MATERIALS AND METHODS: In the 646 chronic CAD patients (72.4% males) coronary angiograms were scored by quantitative assessment using using multiple angiographic scoring system, Traditional risk factors were self reported or measured by standard methods. ABO blood distribution of patients was compared with group of 651 healthy blood donors (74.6% males). RESULTS: Among all ABO blood group patients there was no significant difference between the extent of coronary atherosclerosis with regard to all the three scoring systems: number of affected coronary arteries (P=0.857), Gensini score (P=0.818), and number of segments narrowed >50% (P=0.781). There was no significant difference in ABO blood group distribution between CAD patients and healthy blood donors. Among CAD patients, men with blood group AB were significantly younger than their pairs with non-AB blood groups (P=0.008). Among CAD patients with AB blood group, males <50 yrs were significantly overrepresented when compared with the non-AB groups (P=0.003). CONCLUSIONS: No association between ABO blood groups and the extent of coronary atherosclerosis in Croatian CAD patients is observed. Observation that AB blood group might possibly identify Croatian males at risk to develop the premature CAD has to be tested in larger cohort of patients.

ABO blood groups; Atherosclerosis; Coronary artery disease

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Podaci o izdanju

23 (3)

2013.

351-359

objavljeno

1330-0962

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost