Natriuretic peptides and bradykinin in mouse ischemic brain injury (CROSBI ID 600079)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Dobrivojević, Marina ; Špiranec, Katarina ; Erjavec, Igor ; Gorup, Dunja ; Habek, Nikola ; Hirsch, Jochen R ; Forssmann Wolf-Georg ; Sinđić, Aleksandra
engleski
Natriuretic peptides and bradykinin in mouse ischemic brain injury
Cessation of glucose and oxygen supply after ischemic brain injury leads to apoptotic and nectotic processes, which results in breakdown of the blood-brain barrier and consequent cerebral edema formation. Bradykinin is involved in the formation of cerebral edema increasing the size of brain damage. The aim of our research was clarifying the possible mechanisms of action of natriuretic peptides on bradykinin signaling, and their interaction after ischemic brain injury, since natriuretic peptides decrease brain edema via still unknown mechanisms. The results of this research indicate the existence of an endogenous antagonist of the bradykinin type 2 receptor and the possible protective role of natriuretic peptides in treatment of stroke.
natriuretic peptides; bradykinin; ischemic brain injury
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Podaci o prilogu
44-44.
2013.
objavljeno
Podaci o matičnoj publikaciji
Zagreb: Hrvatsko društvo za neuroznanost ; Hrvatski institut za istraživanje mozga Medicinskog fakulteta Sveučilišta u Zagrebu
Podaci o skupu
4th Croatian Congress of Neuroscience
poster
20.09.2013-21.09.2013
Zagreb, Hrvatska