Water proton NMR relaxation mechanisms in lung tissue (CROSBI ID 195722)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Kveder, Marina ; Zupančič, Ivan ; Lahajnar, Gojmir ; Blinc, Robert ; Šuput, Dusan ; Ailion, D.C. ; Ganesan, K. ; Goodrich, C.
engleski
Water proton NMR relaxation mechanisms in lung tissue
The NMR relaxation times T2, T2, and T1 were measured in isolated rat lungs as functions of external magnetic field B0, temperature, and lung inflation. The observed linear dependence on B0 of the tissue-induced free induction decay rate (T2)−1 provides independent confirmation of the air/water interface model of the lung. Furthermore, measurements of the Larmor frequency dependence of T1, are consistent with a spin- lattice relaxation rate of the form 1/Tl = Aω−1/2+ B as expected for the case in which the relaxation arises from water-biopolymer cross-relaxation, which should be proportional to the surface area of the lung. This prediction was verified by observations of an approximately linear dependence of 1/T1, on transpulmonary pressure and thus on the lung surface area.
NMR diffusion measurements ; fractal ; relaxation
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Podaci o izdanju
7 (4)
1988.
432-441
objavljeno
0740-3194
1522-2594
10.1002/mrm.1910070406