engleski

Family Resemblance in Cardio-Respiratory Traits

Family aggregation of cardio-respiratory traits in the population of Middle Dalmatian islands has been investigated on a random sample of adults. The similarity between first-degree relatives has been quantified by calculating Pearsons product-moment coefficient of correlation. The obtained results have been compared with the corresponding results of other authors, and discussed with respect to the possible influence of genetic and ecological factors on their formation. The highest correlation values within a family have been found in lung function parameters, whereas the lowest correlations have been found for resting pulse rate, and maximum oxygen uptake values. Exceptionally high correlations for lung function parameters among brothers and higher father-offspring correlations for those traits compared with other physiological traits, speak in favor of strong common family environmental influence on lung function traits, acting especially among male family members. The pattern of family correlations for systolic blood pressure resulting in a lesser resemblance in males and in intergenerational pairs, suggests either different environmental influence, either different sensibility - higher in males -to those influence. In contrast, the pattern of family correlations found for diastolic blood pressure, suggests that influences - whether they are primarily genetic or environmental - act on all family members with the same degree.

family analysis; parent-offspring; sibling; heritability; blood pressure; lung function; Dalmatia

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