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Pregled bibliografske jedinice broj: 63999

A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients


Ljubin, Tajana; Žakić-Milas, Danijela; Mimica, Ninoslav; Folnegović-Šmalc, Vera; Makarić, Gordan
A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients // Human psychopharmacology, 15 (2000), 7; 513-519 doi:10.1002/1099-1077(200010)15:73.0.CO ; 2-Y (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 63999 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients

Autori
Ljubin, Tajana ; Žakić-Milas, Danijela ; Mimica, Ninoslav ; Folnegović-Šmalc, Vera ; Makarić, Gordan

Izvornik
Human psychopharmacology (0885-6222) 15 (2000), 7; 513-519

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
schizophrenia ; cognition ; olanzapine ; fluphenazine ; antipsychotic agents ; therapeutic use ; comparative study

Sažetak
The aim of the study was to compare the effect of olanzapine versus fluphenazine treatment on cognitive functioning. Eighteen schizophrenic outpatients, aged 25-61 (average 37 years), all meeting DSM-IV diagnostic criteria for schizophrenia, were included in the study. They were randomly assigned to 22 weeks of either olanzapine or fluphenazine treatment. Certain subscales of the Wechsler Adult Intelligence Scale, the Stroop Neuropsychological Screening Test and the Wisconsin Card Sorting Test were performed. Olanzapine treatment proved to have a beneficial effect on digit-symbol performance and some aspects of executive function. In comparison to the fluphenazine treatment, the olanzapine treatment only showed a beneficial effect in increased percentage of conceptual level responses. Although the results are preliminary, they could implicate that the benefit of olanzapine treatment is primarily related to certain aspects of executive function, i.e. frontal lobe functioning.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Psihologija



POVEZANOST RADA


Projekti:
123004

Ustanove:
Klinika za psihijatriju Vrapče

Citiraj ovu publikaciju

Ljubin, Tajana; Žakić-Milas, Danijela; Mimica, Ninoslav; Folnegović-Šmalc, Vera; Makarić, Gordan
A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients // Human psychopharmacology, 15 (2000), 7; 513-519 doi:10.1002/1099-1077(200010)15:73.0.CO ; 2-Y (međunarodna recenzija, članak, znanstveni)
Ljubin, T., Žakić-Milas, D., Mimica, N., Folnegović-Šmalc, V. & Makarić, G. (2000) A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients. Human psychopharmacology, 15 (7), 513-519 doi:10.1002/1099-1077(200010)15:73.0.CO ; 2-Y.
@article{article, year = {2000}, pages = {513-519}, DOI = {10.1002/1099-1077(200010)15:73.0.CO ; 2-Y}, keywords = {schizophrenia, cognition, olanzapine, fluphenazine, antipsychotic agents, therapeutic use, comparative study}, journal = {Human psychopharmacology}, doi = {10.1002/1099-1077(200010)15:73.0.CO ; 2-Y}, volume = {15}, number = {7}, issn = {0885-6222}, title = {A preliminary study of the Comparative Effects of Olanzapine and Fluphenazine on Cognition in Schizophrenic Patients}, keyword = {schizophrenia, cognition, olanzapine, fluphenazine, antipsychotic agents, therapeutic use, comparative study} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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