Monitoring the Healing Process of Rat Bones Using Raman Spectroscopy (CROSBI ID 194383)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Gamulin, Ozren ; Serec, Kristina ; Bilić, V. ; Balarin, Maja ; Kosović, Marin ; Drmić, Domagoj ; Brčić, Luka ; Seiwerth, Sven ; Sikirić, Predrag
engleski
Monitoring the Healing Process of Rat Bones Using Raman Spectroscopy
The healing effect of BPC 157 on rat femoral head osteonecrosis was monitored by Raman spectroscopy. Three groups of rats were defined: an injured group treated with BPC 157 (10 μg/kg/daily ip), an injured control group (treated with saline, 5 ml/kg/daily ip), and an uninjured healthy group. The spectra were recorded and the healing effect assessed on samples harvested from animals which were sacrificed 3 and 6 weeks after being injured. The statistical analysis of the recorded spectra showed statistical differences between the BPC 157-treated, control, and healthy groups of animals. In particular, after 6 weeks the spectral resemblance between the healthy and BPC 157 samples indicated a positive BPC 157 influence on the healing process of rat femoral head.
Raman spectroscopy; Femoral head osteonecrosis; BPC 157 healing effects; Bone healing; PCA
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Podaci o izdanju
1044
2013.
308-313
objavljeno
0022-2860
10.1016/j.molstruc.2013.01.049
