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Monitoring the Healing Process of Rat Bones Using Raman Spectroscopy


Gamulin, Ozren; Serec, Kristina; Bilić, V.; Balarin, Maja; Kosović, Marin; Drmić, Domagoj; Brčić, Luka; Seiwerth, Sven; Sikirić, Predrag
Monitoring the Healing Process of Rat Bones Using Raman Spectroscopy // Journal of molecular structure, 1044 (2013), 308-313 doi:10.1016/j.molstruc.2013.01.049 (međunarodna recenzija, članak, znanstveni)


Naslov
Monitoring the Healing Process of Rat Bones Using Raman Spectroscopy

Autori
Gamulin, Ozren ; Serec, Kristina ; Bilić, V. ; Balarin, Maja ; Kosović, Marin ; Drmić, Domagoj ; Brčić, Luka ; Seiwerth, Sven ; Sikirić, Predrag

Izvornik
Journal of molecular structure (0022-2860) 1044 (2013); 308-313

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Raman spectroscopy; Femoral head osteonecrosis; BPC 157 healing effects; Bone healing; PCA

Sažetak
The healing effect of BPC 157 on rat femoral head osteonecrosis was monitored by Raman spectroscopy. Three groups of rats were defined: an injured group treated with BPC 157 (10 μg/kg/daily ip), an injured control group (treated with saline, 5 ml/kg/daily ip), and an uninjured healthy group. The spectra were recorded and the healing effect assessed on samples harvested from animals which were sacrificed 3 and 6 weeks after being injured. The statistical analysis of the recorded spectra showed statistical differences between the BPC 157-treated, control, and healthy groups of animals. In particular, after 6 weeks the spectral resemblance between the healthy and BPC 157 samples indicated a positive BPC 157 influence on the healing process of rat femoral head.

Izvorni jezik
Engleski

Znanstvena područja
Fizika



POVEZANOST RADA


Projekt / tema
108-1080134-3105 - Mehanizmi narušavanja strukture lipoproteina djelovanjem vanjskih čimbenika (Ozren Gamulin, )
108-1080399-0383 - Muški i ženski spolni sustav: razvoj, normalna histofiziologija i neplodnost (Davor Ježek, )
108-1083570-3635 - Pentadekapeptid BPC 157 - daljnja istraživanja (Predrag Sikirić, )
108-1083570-3643 - Kvantitativna analiza i prijenos slike u patologiji (Sven Seiwerth, )

Ustanove
Medicinski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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