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The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe


Novokmet, Natalija; Marjanović, Damir; Havaš Auguštin, Dubravka; Šarac, Jelena; Šarić, Tena; Škaro, Vedrana; Projić, Petar; Lauc, Gordan; Vidovič, Maruška; Rudan, Pavao
The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe // PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine / Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses (ur.).
Zagreb: ISABS - International Society for Applied Biological Sciences, 2013. str. 218-218 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe

Autori
Novokmet, Natalija ; Marjanović, Damir ; Havaš Auguštin, Dubravka ; Šarac, Jelena ; Šarić, Tena ; Škaro, Vedrana ; Projić, Petar ; Lauc, Gordan ; Vidovič, Maruška ; Rudan, Pavao

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine / Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses - Zagreb : ISABS - International Society for Applied Biological Sciences, 2013, 218-218

ISBN
978-953-57695-0-7

Skup
The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine

Mjesto i datum
Split, Hrvatska, 24-28.06.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
population substructure; forensic parameters; STR markers; DNA database; South-Eastern Europe

Sažetak
Population substructuring due to organization into small groups has probably been a characteristic demographic feature during the vast majority of human population history, and persists today to a greater or lesser extent in many rural areas. As some of the few persisting isolates among contemporary South-Eastern European (SE European) human groups, isolated Croatian islands are among the most suitable models for theoretical analyses differentiation and substructuring. In this study the data obtained by means of the analysis of 9 autosomal STR loci of microsatellite DNA in Croatian islands and Slovenian populations were integrated with the published data from other Croatian islands and wide SE European region. The sample was defined hierarchically and the influence of isolation of the Croatian insular populations on substructuring of the population of Croatia, as well as the influence of the regional population groups on substructuring of South- Eastern Europe was detected. Due to the decreased influence of endogamy, lower genetic differentiation was detected at the higher level of grouping of SE European populations (FST = 0, 002) than at the level of sub-populations of Croatia (FST = 0, 005). Finally, the influence of substructuring of the aforementioned levels on the calculation of forensic statistical parameters was determined. It was found that the isolation of Croatian insular populations affects the value of forensic parameters. This led to the modelling of adequate sampling of the entire population when creating the DNA database of genetic STR markers that would reflect all characteristics of its subpopulations.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Etnologija i antropologija



POVEZANOST RADA


Projekt / tema
196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Pavao Rudan, )

Ustanove
Institut za antropologiju,
GENOS d.o.o.

Citiraj ovu publikaciju

Novokmet, Natalija; Marjanović, Damir; Havaš Auguštin, Dubravka; Šarac, Jelena; Šarić, Tena; Škaro, Vedrana; Projić, Petar; Lauc, Gordan; Vidovič, Maruška; Rudan, Pavao
The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe // PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine / Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses (ur.).
Zagreb: ISABS - International Society for Applied Biological Sciences, 2013. str. 218-218 (poster, međunarodna recenzija, sažetak, znanstveni)
Novokmet, N., Marjanović, D., Havaš Auguštin, D., Šarac, J., Šarić, T., Škaro, V., Projić, P., Lauc, G., Vidovič, M. & Rudan, P. (2013) The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe. U: Vuk-Pavlović, S., Primorac, D. & Schanfield, M. (ur.)PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine.
@article{article, year = {2013}, pages = {218-218}, keywords = {population substructure, forensic parameters, STR markers, DNA database, South-Eastern Europe}, isbn = {978-953-57695-0-7}, title = {The influence of populations substructuring on statistical forensic parameters of genetic STR markers in the area of South-Eastern Europe}, keyword = {population substructure, forensic parameters, STR markers, DNA database, South-Eastern Europe}, publisher = {ISABS - International Society for Applied Biological Sciences}, publisherplace = {Split, Hrvatska} }