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izvor podataka: crosbi

Hepatoid adenocarcinoma of the stomach : case report and short notes on immuno histochemical markers (CROSBI ID 194136)

Prilog u časopisu | prikaz, osvrt, kritika

Augustin, Goran ; Jelinčić, Željko ; Tentor, Damir ; Majerović, Mate ; Matošević, Petar Hepatoid adenocarcinoma of the stomach : case report and short notes on immuno histochemical markers // Acta gastro-enterologica belgica (Ed. multilingue), 72 (2009), 2; 253-256

Podaci o odgovornosti

Augustin, Goran ; Jelinčić, Željko ; Tentor, Damir ; Majerović, Mate ; Matošević, Petar

engleski

Hepatoid adenocarcinoma of the stomach : case report and short notes on immuno histochemical markers

Hepatoid adenocarcinoma of the stomach is a rare type of gastric carcinoma with an extremely poor prognosis. We describe a 72- year-old man who underwent esophagogastroduodenoscopy which revealed 50 mm exulcerated lesion with a central necrosis on the lesser curvature and the posterior wall of the body of the stomach. Gastric biopsy revealed a poorly differentiated (anaplastic) adenocarcinoma. The serum level of alpha-fetoprotein (AFP) was (3220 ng/mL). After diagnosis of AFP-producing gastric adenocarcinoma, total gastrectomy, with splenectomy, was performed. The tumor showed immunohistochemical positivity for AFP and Hep Par 1. According to these histopathological and immunohistochemical findings, the tumor was diagnosed as hepatoid adenocarcinoma. At 24 months postoperatively the patient is still alive without metastatic disease on repeated abdominal CTs. Because of the poor prognosis for this histological type of tumor, accurate diagnosis of hepatoid adenocarcinoma is important, and long-term follow-up is required.

gastric cancer; hepatoid adenocarcinoma; aAlpha-fetoprotein- producing cancer; hepatocyte-paraffin-1 positive cancer

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Podaci o izdanju

72 (2)

2009.

253-256

objavljeno

0001-5644

Povezanost rada

Temeljne medicinske znanosti, Kliničke medicinske znanosti

Indeksiranost