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Pregled bibliografske jedinice broj: 634229

Ulipristal acetate in emergency contraception


Šprem Goldštajn, Marina; Pavičić Baldani, Dinka; Škrgatić, Lana; Radaković, Branko; Vrčić, Hrvoje; Čanić, Tomislav
Ulipristal acetate in emergency contraception // Collegium antropologicum, 38 (2014), 1; 379-384 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 634229 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Ulipristal acetate in emergency contraception

Autori
Šprem Goldštajn, Marina ; Pavičić Baldani, Dinka ; Škrgatić, Lana ; Radaković, Branko ; Vrčić, Hrvoje ; Čanić, Tomislav

Izvornik
Collegium antropologicum (0350-6134) 38 (2014), 1; 379-384

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
emergency contraception; ulipristal acetate.

Sažetak
Despite the widespread availability of highly effective methods of contraception, unintended pregnancy is common. Unplanned pregnancies have been linked to a range of health, social and economic consequences . Emergency contraception reduces risk of pregnancy after unprotected intercourse, and represents an opportunity to decrease number of unplanned pregnancies and abortions. Emergency contraception pills (ECP) prevent pregnancy by delaying or inhibiting ovulation, without interfering with post fertilization events. If pregnancy has already occurred, ECPs will not be effective, therefore ECPs are not abortificants. Ulipristal acetate (17α-acetoxy-11β-(4N-N, N-dymethilaminophenyl)-19-norpregna-4, 9-diene-3, 20-dione) is the first drug that was specifically developed and licensed for use as an emergency contraceptive. It is an orally active, synthetic, selective progesterone modulator that acts by binding with high affinity to the human progesterone receptor where it has both antagonist and partial agonist effects. It is a new molecular entity and the first compound in a new pharmacological class defined by the pristal stem. Up on the superior clinical efficacy evidence, UPA has been quickly recognized as the most effective emergency contraceptive pill, and recently recommended as the first prescription choice for all women regardless of the age and timing after intercourse. This article provides literature review of UPA and its role in emergency contraception.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-0000000-0388 - Etiologija i patogeneza PCOS - odabir terapije i metaboličke posljedice (Pavičić Baldani, Dinka, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb


Citiraj ovu publikaciju:

Šprem Goldštajn, Marina; Pavičić Baldani, Dinka; Škrgatić, Lana; Radaković, Branko; Vrčić, Hrvoje; Čanić, Tomislav
Ulipristal acetate in emergency contraception // Collegium antropologicum, 38 (2014), 1; 379-384 (međunarodna recenzija, članak, znanstveni)
Šprem Goldštajn, M., Pavičić Baldani, D., Škrgatić, L., Radaković, B., Vrčić, H. & Čanić, T. (2014) Ulipristal acetate in emergency contraception. Collegium antropologicum, 38 (1), 379-384.
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@article{article, author = {\v{S}prem Gold\v{s}tajn, Marina and Pavi\v{c}i\'{c} Baldani, Dinka and \v{S}krgati\'{c}, Lana and Radakovi\'{c}, Branko and Vr\v{c}i\'{c}, Hrvoje and \v{C}ani\'{c}, Tomislav}, year = {2014}, pages = {379-384}, keywords = {emergency contraception, ulipristal acetate.}, journal = {Collegium antropologicum}, volume = {38}, number = {1}, issn = {0350-6134}, title = {Ulipristal acetate in emergency contraception}, keyword = {emergency contraception, ulipristal acetate.} }

Časopis indeksira:


  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • EMBASE (Excerpta Medica)





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