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Pregled bibliografske jedinice broj: 634111

Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population


Pavičić Baldani, Dinka; Škrgatić, Lana; Šprem Goldštajn, Marina; Vrčić, Hrvoje; Čanić, Tomislav; Strelec, Mihajlo
Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population // Collegium antropologicum, 37 (2013), 2; 465-470 (međunarodna recenzija, članak, znanstveni)


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Naslov
Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population

Autori
Pavičić Baldani, Dinka ; Škrgatić, Lana ; Šprem Goldštajn, Marina ; Vrčić, Hrvoje ; Čanić, Tomislav ; Strelec, Mihajlo

Izvornik
Collegium antropologicum (0350-6134) 37 (2013), 2; 465-470

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
PCOS; obesity; hyperandrogenism; insulin resistance; dyslipidemia

Sažetak
Obesity has a deteriorating impact on women with PCOS, although prevalence and the impact of specific traits of PCOS remain inconstant in different populations. Therefore, the aim of this study was to explore the differences in clinical, hormonal and metabolic features between obese and nonobese Croatian women diagnosed as having PCOS according to Rotterdam consensus criteria. The study included 74 obese and 208 nonobese women with PCOS. Clinical, biochemical and metabolic variables were compared among those PCOS subgroups. Obese subjects with PCOS had a higher risk of developing oligo- amenorrhea (OR 3.7 ; 95% CI, 1.1-12.5) and lower risk for developing hirsutism and acne (OR 0.2 ; 95% CI, 0.1-0.3 and OR 0.8 ; 95% CI 0.5-1.4, respectively). Obese PCOS subjects also had a higher risk of developing hyperandrogenemia (OR 2.5 ; CI 95% 0.9-6.7), insulin resistance (OR 4.5 ; CI 95%, 2.6-7.9), hypercholesterolemia (OR 5.0, CI 95% 2.5-10.2), hypertriglyceridemia (OR 5.2 ; 95% CI, 2.9-9.2) as well as elevated serum CRP levels (OR 4.1 ; 95% CI 1.4-12.2) compared to nonobese PCOS women. In conclusion, nonobese Croatian women with PCOS are more inclined to cosmetic problems associated with PCOS then metabolic ones. This is the first study to report the impact of obesity on acne and irregular menses as a study outcome. Obesity deteriorates menstrual regularity, insulin sensitivity and lipid profile in Croatian women with PCOS ; therefore one of the fundamental treatment strategies of PCOS should be obesity prevention.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
108-0000000-0388 - Etiologija i patogeneza PCOS - odabir terapije i metaboličke posljedice (Pavičić Baldani, Dinka, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Poveznice na cjeloviti tekst rada:

Hrčak

Citiraj ovu publikaciju:

Pavičić Baldani, Dinka; Škrgatić, Lana; Šprem Goldštajn, Marina; Vrčić, Hrvoje; Čanić, Tomislav; Strelec, Mihajlo
Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population // Collegium antropologicum, 37 (2013), 2; 465-470 (međunarodna recenzija, članak, znanstveni)
Pavičić Baldani, D., Škrgatić, L., Šprem Goldštajn, M., Vrčić, H., Čanić, T. & Strelec, M. (2013) Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population. Collegium antropologicum, 37 (2), 465-470.
@article{article, author = {Pavi\v{c}i\'{c} Baldani, Dinka and \v{S}krgati\'{c}, Lana and \v{S}prem Gold\v{s}tajn, Marina and Vr\v{c}i\'{c}, Hrvoje and \v{C}ani\'{c}, Tomislav and Strelec, Mihajlo}, year = {2013}, pages = {465-470}, keywords = {PCOS, obesity, hyperandrogenism, insulin resistance, dyslipidemia}, journal = {Collegium antropologicum}, volume = {37}, number = {2}, issn = {0350-6134}, title = {Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population}, keyword = {PCOS, obesity, hyperandrogenism, insulin resistance, dyslipidemia} }
@article{article, author = {Pavi\v{c}i\'{c} Baldani, Dinka and \v{S}krgati\'{c}, Lana and \v{S}prem Gold\v{s}tajn, Marina and Vr\v{c}i\'{c}, Hrvoje and \v{C}ani\'{c}, Tomislav and Strelec, Mihajlo}, year = {2013}, pages = {465-470}, keywords = {PCOS, obesity, hyperandrogenism, insulin resistance, dyslipidemia}, journal = {Collegium antropologicum}, volume = {37}, number = {2}, issn = {0350-6134}, title = {Clinical, hormonal and metabolic characteristics of polycystic ovary syndrome among obese and non obese women in Croatian population}, keyword = {PCOS, obesity, hyperandrogenism, insulin resistance, dyslipidemia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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