engleski

Metastasis - recent scientific insights and challenging new therapeutic approaches

Majority of cancer patients never die from the original disease – primary tumor - but from the metastasis that disseminate throughout the body. Although they disseminate in millions actually few of them succeeded in their journey and achieve their main goal – form a distant metastatic colony which is able to thrive in an inhospitable environment of an unrelated tissue. This review will summarize in brief some of the recent advances in cancer invasion and metastasis investigations and possibilities in using these findings for the benefit of cancer patients.

metastasis ; epithelial-mesenchymal transition ; cancer stem cells ; metastasis suppressor genes ; dormancy

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