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Pregled bibliografske jedinice broj: 629588

Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion


Schmidt, Daniel; Bihr, Timo; Seifert, Udo; Smith, Ana-Sunčana
Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion // Europhysics Letters, 99 (2012), 3; 38003-1 doi:10.1209/0295-5075/99/38003 (međunarodna recenzija, pismo, znanstveni)


Naslov
Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion

Autori
Schmidt, Daniel ; Bihr, Timo ; Seifert, Udo ; Smith, Ana-Sunčana

Izvornik
Europhysics Letters (0295-5075) 99 (2012), 3; 38003-1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni

Ključne riječi
Membrane ; adhesion

Sažetak
We analyze the stability of micro-domains of ligand-receptor bonds that mediate the adhesion of biological model membranes. After evaluating the effects of membrane fluctuations on the binding affinity of a single bond, we characterize the organization of bonds within the domains by theoretical means. In a large range of parameters, we find the commonly suggested dense packing to be separated by a free energy barrier from a regime in which bonds are sparsely distributed. If bonds are mobile, a coexistence of the two regimes should emerge, which agrees with recent experimental observations.

Izvorni jezik
Engleski

Znanstvena područja
Fizika



POVEZANOST RADA


Projekt / tema
098-1191344-2860 - Proučavanje biomakromolekula računalnim metodama i razvoj novih algoritama (Sanja Tomić, )

Ustanove
Institut "Ruđer Bošković", Zagreb

Autor s matičnim brojem:
Ana Sunčana Smith, (280014)

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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