Pregled bibliografske jedinice broj: 629588
Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion
Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion // Europhysics Letters, 99 (2012), 3; 38003-1 doi:10.1209/0295-5075/99/38003 (međunarodna recenzija, pismo, znanstveni)
CROSBI ID: 629588 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion
Autori
Schmidt, Daniel ; Bihr, Timo ; Seifert, Udo ; Smith, Ana-Sunčana
Izvornik
Europhysics Letters (0295-5075) 99
(2012), 3;
38003-1
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni
Ključne riječi
membrane ; adhesion
Sažetak
We analyze the stability of micro-domains of ligand-receptor bonds that mediate the adhesion of biological model membranes. After evaluating the effects of membrane fluctuations on the binding affinity of a single bond, we characterize the organization of bonds within the domains by theoretical means. In a large range of parameters, we find the commonly suggested dense packing to be separated by a free energy barrier from a regime in which bonds are sparsely distributed. If bonds are mobile, a coexistence of the two regimes should emerge, which agrees with recent experimental observations.
Izvorni jezik
Engleski
Znanstvena područja
Fizika
POVEZANOST RADA
Projekti:
098-1191344-2860 - Proučavanje biomakromolekula računalnim metodama i razvoj novih algoritama (Tomić, Sanja, MZOS ) ( CroRIS)
Ustanove:
Institut "Ruđer Bošković", Zagreb
Profili:
Ana Sunčana Smith
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus