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Pregled bibliografske jedinice broj: 627787

The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick


Miletić, Antonija; Krmpotić, Astrid; Jonjić, Stipan
The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick // European journal of immunology, 43 (2013), 4; 867-877 doi:10.1002/eji.201243101 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick

Autori
Miletić, Antonija ; Krmpotić, Astrid ; Jonjić, Stipan

Izvornik
European journal of immunology (0014-2980) 43 (2013), 4; 867-877

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
MCMV; NK cells; innate immunity

Sažetak
NK cells are innate lymphocytes that play a key role in the control of various viral infections. Recent studies indicate that NK cells may acquire some features of adaptive immune cells, including the formation of long-lived memory cells. A large and growing body of data indicates that NK cells regulate the adaptive immune response as well. The function and the activation status of NK cells are tightly regulated by signals induced by a broad range of inhibitory and activating cell surface receptors and cytokines released by other immune cells. Here, we review the function of mouse NK-cell receptors involved in virus control and in the regulation of the adaptive immune response. In addition, we discuss viral strategies used to evade NK-cell-mediated control during infection. Finally, the role of several activating Ly49 receptors specific for mouse cytomegalovirus (MCMV), as well as some controversial issues in the field, will be discussed.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
062-0621261-1263 - Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru (Jonjić, Stipan, MZOS ) ( POIROT)
062-0621261-1268 - Uloga imunosubverzivnih citomegalovirusnih gena u latenciji (Krmpotić, Astrid, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka

Profili:

Avatar Url Stipan Jonjić (autor)

Avatar Url Astrid Krmpotić (autor)

Citiraj ovu publikaciju

Miletić, Antonija; Krmpotić, Astrid; Jonjić, Stipan
The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick // European journal of immunology, 43 (2013), 4; 867-877 doi:10.1002/eji.201243101 (međunarodna recenzija, pregledni rad, znanstveni)
Miletić, A., Krmpotić, A. & Jonjić, S. (2013) The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick. European journal of immunology, 43 (4), 867-877 doi:10.1002/eji.201243101.
@article{article, year = {2013}, pages = {867-877}, DOI = {10.1002/eji.201243101}, keywords = {MCMV, NK cells, innate immunity}, journal = {European journal of immunology}, doi = {10.1002/eji.201243101}, volume = {43}, number = {4}, issn = {0014-2980}, title = {The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick}, keyword = {MCMV, NK cells, innate immunity} }
@article{article, year = {2013}, pages = {867-877}, DOI = {10.1002/eji.201243101}, keywords = {MCMV, NK cells, innate immunity}, journal = {European journal of immunology}, doi = {10.1002/eji.201243101}, volume = {43}, number = {4}, issn = {0014-2980}, title = {The evolutionary arms race between NK cells and viruses: Who gets the short end of the stick}, keyword = {MCMV, NK cells, innate immunity} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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