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Pregled bibliografske jedinice broj: 620061

The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation


Alebić, Miro Šimun; Stojanović, Nataša; Žuvić-Butorac, Marta
The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation // International Journal of Endocrinology, 2013 (2013), 637919-1 doi:10.1155/2013/637919 (međunarodna recenzija, članak, znanstveni)


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Naslov
The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation

Autori
Alebić, Miro Šimun ; Stojanović, Nataša ; Žuvić-Butorac, Marta

Izvornik
International Journal of Endocrinology (1687-8337) 2013 (2013); 637919-1

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
DHEAS; GnRH antagonist; clinical pregnancy; anti-Müllerian hormone

Sažetak
Objective was to investigate the endocrine and/or clinical characteristics of women with low anti-Müllerian hormone (AMH) that could improve the accuracy of IVF outcome prediction based on the female age alone prior to the first GnRH antagonist IVF cycle. Medical records of 129 patients with low AMH level (<6.5 pmol/L) who underwent their first GnRH antagonist ovarian stimulation protocol for IVF/ICSI were retrospectively analyzed. The main outcome measure was the area under the ROC curve (AUC-ROC) for the models combining age and other potential predictive factors for the clinical pregnancy. Clinical pregnancy rate per initiated cycles (CPR) was 11.6%. For the prediction of clinical pregnancy, DHEAS and age showed AUC-ROC of 0.726 (95%CI 0.641-0.801) and 0.662 (95%CI 0.573-0.743), respectively (P=0.522). The predictive accuracy of the model combining age and DHEAS (AUC-ROC 0.796 ; 95%CI 0.716-0.862) was significantly higher compared to that of age alone (P=0.013). In patients <37.5 years with DHEAS >5.7 pmol/L, 60% (9/15) of all pregnancies were achieved with CPR of 37.5%. DHEAS appears to be predictive for clinical pregnancy in younger women (<37.5 years) with low AMH after the first GnRH antagonist IVF cycle. Therefore, DHEAS-age model could refine the pretreatment counseling on pregnancy prospects following IVF.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinička bolnica "Merkur"

Profili:

Avatar Url Nataša Stojanović (autor)

Avatar Url Marta Žuvić (autor)

Poveznice na cjeloviti tekst rada:

doi www.hindawi.com

Citiraj ovu publikaciju:

Alebić, Miro Šimun; Stojanović, Nataša; Žuvić-Butorac, Marta
The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation // International Journal of Endocrinology, 2013 (2013), 637919-1 doi:10.1155/2013/637919 (međunarodna recenzija, članak, znanstveni)
Alebić, M., Stojanović, N. & Žuvić-Butorac, M. (2013) The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation. International Journal of Endocrinology, 2013, 637919-1 doi:10.1155/2013/637919.
@article{article, year = {2013}, pages = {637919-1-637919-7}, DOI = {10.1155/2013/637919}, keywords = {DHEAS, GnRH antagonist, clinical pregnancy, anti-M\"{u}llerian hormone}, journal = {International Journal of Endocrinology}, doi = {10.1155/2013/637919}, volume = {2013}, issn = {1687-8337}, title = {The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation}, keyword = {DHEAS, GnRH antagonist, clinical pregnancy, anti-M\"{u}llerian hormone} }
@article{article, year = {2013}, pages = {637919-1-637919-7}, DOI = {10.1155/2013/637919}, keywords = {DHEAS, GnRH antagonist, clinical pregnancy, anti-M\"{u}llerian hormone}, journal = {International Journal of Endocrinology}, doi = {10.1155/2013/637919}, volume = {2013}, issn = {1687-8337}, title = {The IVF outcome counseling based on the model combining DHEAS and age in patients with low AMH prior to the first cycle of GnRH antagonist protocol of ovarian stimulation}, keyword = {DHEAS, GnRH antagonist, clinical pregnancy, anti-M\"{u}llerian hormone} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Uključenost u ostale bibliografske baze podataka::


  • Biological Sciences
  • Calcium and Calcified Tissue Abstracts
  • CA Search (Chemical Abstracts)
  • EMBASE (Excerpta Medica)
  • BioMedSearch
  • EBSCO Academic Source Complete
  • Journal Citation Reports: Science Edition
  • PubMed
  • Scopus


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