Influence of Active Dendrites on Firing Patterns in a Retinal Ganglion Cell Model (CROSBI ID 594342)
Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Guo, Tianruo ; Tsai, David ; Sovilj, Siniša ; Morley, John William ; Suaning, Gregg ; Lovell, Nigel ; Dokos, Socrates ;
engleski
Influence of Active Dendrites on Firing Patterns in a Retinal Ganglion Cell Model
Active regional conductances and inhomogeneous distribution of membrane ionic channels in dendrites influence the integration of synaptic inputs in cortical neurons. How these properties shape the response properties of retinal ganglion cells (RGC) in the mammalian retina has remained largely unexplored. In this study, we used a morphologically-realistic RGC computational model to study how active dendritic properties contribute to neural behaviors. Our simulations suggest that the dendritic distribution of voltage-gated ionic channels strongly influences RGC firing patterns, indicating their important contribution to neuronal function.
Ionic modeling; Physiological systems; Parameter estimation
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
4557-4560.
2013.
objavljeno
Podaci o matičnoj publikaciji
Engineering in Medicine and Biology Society (EMBC), 2013 Annual International Conference of the IEEE
Toshiyo Tamura, Nigel Lovell
IEEE EMBC
Podaci o skupu
35th Annual International IEEE EMBS Conference of the IEEE Engineering in Medicine and Biology Society
poster
03.07.2013-07.07.2013
Osaka, Japan