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Pregled bibliografske jedinice broj: 616732

Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study


Gašparović, Stojanka; Rustemović, Nadan; Opačić, Milorad; Premužić, Marina; Korušić, Anđelko; Božikov, Jadranka; Bates, Tamara
Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study // World journal of gastroenterology, 12 (2006), 2; 327-330 (međunarodna recenzija, kratko priopcenje, znanstveni)


CROSBI ID: 616732 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study

Autori
Gašparović, Stojanka ; Rustemović, Nadan ; Opačić, Milorad ; Premužić, Marina ; Korušić, Anđelko ; Božikov, Jadranka ; Bates, Tamara

Izvornik
World journal of gastroenterology (1007-9327) 12 (2006), 2; 327-330

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
endoscopy; conscious sedation; propofol; hemodynamic adverse effects

Sažetak
The optimal administration of conscious sedation and patient monitoring during gastrointestinal endoscopy has not been well emphasized. Benzodiazepines are most commonly used, often with pethidine. Anesthetic agents are less frequently used because oversedation may induce respiratory depression, hypotension, and other cardiopulmonary complications. In this study we analysed the hemodynamic and respiratory effects of propofol on patients undergoing gastroscopy and colonoscopy. In this prospective study, conducted over a period of three years, 1, 104 patients referred for a same day GI endoscopy procedure were analyzed. All patients were given a propofol bolus (0.5-1.5 mg/kg). Arterial blood pressure (BP) was monitored at 3 min intervals and heart rate and oxygen saturation (SpO2) were recorded continuously by pulse oximetry. Analyzed data acquisition was carried out before, during, and after the procedure. A statistically significant reduction in mean arterial pressure was demonstrated (p<0.001) when compared to pre-intervention values, but severe hypotension, defined as a systolic blood pressure below 60 mmHg, was noted in only 5 patients (0.5%). Oxygen saturation decreased from 96.5% to 94.4 % (p<0.001). A critical decrease in oxygen saturation (<90%) was documented in 27 patients (2.4%). Our results showed that propofol provided good sedation with excellent pain control, a short recovery time and no significant hemodynamic side effects. All high risk patients (ASA III group) require monitoring and care of an anesthesiologist.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Zagreb,
Klinička bolnica "Dubrava",
Klinički bolnički centar Zagreb

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada www.wjgnet.com

Citiraj ovu publikaciju:

Gašparović, Stojanka; Rustemović, Nadan; Opačić, Milorad; Premužić, Marina; Korušić, Anđelko; Božikov, Jadranka; Bates, Tamara
Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study // World journal of gastroenterology, 12 (2006), 2; 327-330 (međunarodna recenzija, kratko priopcenje, znanstveni)
Gašparović, S., Rustemović, N., Opačić, M., Premužić, M., Korušić, A., Božikov, J. & Bates, T. (2006) Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study. World journal of gastroenterology, 12 (2), 327-330.
@article{article, year = {2006}, pages = {327-330}, keywords = {endoscopy, conscious sedation, propofol, hemodynamic adverse effects}, journal = {World journal of gastroenterology}, volume = {12}, number = {2}, issn = {1007-9327}, title = {Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study}, keyword = {endoscopy, conscious sedation, propofol, hemodynamic adverse effects} }
@article{article, year = {2006}, pages = {327-330}, keywords = {endoscopy, conscious sedation, propofol, hemodynamic adverse effects}, journal = {World journal of gastroenterology}, volume = {12}, number = {2}, issn = {1007-9327}, title = {Clinical analysis of propofol deep sedation for 1, 104 patients undergoing gastrointestinal endoscopic procedures : A three year prospective study}, keyword = {endoscopy, conscious sedation, propofol, hemodynamic adverse effects} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • Scopus





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