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Pregled bibliografske jedinice broj: 615179

Innate immunity to cytomegalovirus in the murine model


Vidal, Silvia; Krmpotić, Astrid; Pyzik, Michal; Jonjić, Stipan
Innate immunity to cytomegalovirus in the murine model // Cytomegaloviruses : from molecular pathogenesis to intervention / Reddehase, Matthias (ur.).
Njemačka: Caister academic press, 2013. str. 192-214


Naslov
Innate immunity to cytomegalovirus in the murine model

Autori
Vidal, Silvia ; Krmpotić, Astrid ; Pyzik, Michal ; Jonjić, Stipan

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, ostalo

Knjiga
Cytomegaloviruses : from molecular pathogenesis to intervention

Urednik/ci
Reddehase, Matthias

Izdavač
Caister academic press

Grad
Njemačka

Godina
2013

Raspon stranica
192-214

ISBN
978-1-908230-18-8

Ključne riječi
innate immunity, cytomegalovirus, murine model

Sažetak
Cells of the innate immune system, including macrophages, DCs and NK cells play an important role in the control of viral infection before the induction of a specific immune response, of which generation they are also crucial. The infection of mice with MCMV as a model of HCMV infection has been particularly informative in elucidating the role of innate and adaptive immune response mechanisms during infection. NK cells are considered the most important effector cells in early CMV surveillance. An evolutionary struggle between NK cells and CMVs can be inferred from the existence of a broad range of viral mechanisms designed to compromise NK-cell function. This chapter describes major innate immune response mechanisms involved in control of MCMV, with an emphasis on NK-cell mediated viral detection as well as virally-encoded immune evasion mechanisms.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekt / tema
062-0621261-1263 - Molekularni mehanizmi citomegalovirusnog izmicanja imunološkom nadzoru (Stipan Jonjić, )
062-0621261-1268 - Uloga imunosubverzivnih citomegalovirusnih gena u latenciji (Astrid Krmpotić, )

Ustanove
Medicinski fakultet, Rijeka

Profili:

Avatar Url Astrid Krmpotić (autor)

Avatar Url Stipan Jonjić (autor)

Citiraj ovu publikaciju

Vidal, Silvia; Krmpotić, Astrid; Pyzik, Michal; Jonjić, Stipan
Innate immunity to cytomegalovirus in the murine model // Cytomegaloviruses : from molecular pathogenesis to intervention / Reddehase, Matthias (ur.).
Njemačka: Caister academic press, 2013. str. 192-214
Vidal, S., Krmpotić, A., Pyzik, M. & Jonjić, S. (2013) Innate immunity to cytomegalovirus in the murine model. U: Reddehase, M. (ur.) Cytomegaloviruses : from molecular pathogenesis to intervention. Njemačka, Caister academic press, str. 192-214.
@inbook{inbook, editor = {Reddehase, M.}, year = {2013}, pages = {192-214}, keywords = {innate immunity, cytomegalovirus, murine model}, isbn = {978-1-908230-18-8}, title = {Innate immunity to cytomegalovirus in the murine model}, keyword = {innate immunity, cytomegalovirus, murine model}, publisher = {Caister academic press}, publisherplace = {Njema\v{c}ka} }