engleski

Genetic variation of six X chromosomal STR loci in Bayash Roma samples from Croatia

X chromosome STRs are another tool for exploring different populations and their genetic characteristics and have been more and more used in recent years to accompany autosomal and uniparental markers data in population genetics. In the present study, six X chromosomal microsatellite loci (DXS983, DXS1225, DXS8092, DXS986, DXS1066 and DXS8082) were used to analyze 79 samples of unrelated male individuals from two Bayash Roma populations living in Croatia. The number of alleles for the studied loci ranged from 5-8 in Međimurje and 4–9 in Baranja, while the overall gene diversity values varied from 0.9673 to 0.9926, respectively. The most informative marker was DXS8092 (0.80628), whereas DXS1066 (0.18103) was the less informative one. Our results show that there is a statistically significant difference between Baranja and Međimurje samples based on haplotype frequencies, which conforms to our previously obtained data from uniparental markers. The coefficient of genetic differentiation (FST) is 1.6%, which is lower than in mitochondrial DNA (6%) or Y chromosome (2%). All of these results indicate that although Baranja and Međimurje Bayash Roma populations are part of the bigger Vlax Roma group and thus share similar background and origin, they clearly differ among themselves ; however, future investigations should be undertaken to determine whether this difference is a reflection of separation prior to arriving in Croatia or a result of the past two centuries of strong genetic isolation on their current living location.

Roma (Gypsies); Bayash; X chromosome; short tandem repeats (STR)

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