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Pregled bibliografske jedinice broj: 607021

Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria


Vučić Lovrenčić, Marijana; Radišić Biljak, Vanja; Božičević, Sandra; Prašek, Manja; Pavković, Pajica; Knotek, Mladen
Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria // Clinical biochemistry, 45 (2012), 18; 1694-1696 doi:10.1016/j.clinbiochem.2012.07.115 (međunarodna recenzija, kratko priopcenje, znanstveni)


CROSBI ID: 607021 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria

Autori
Vučić Lovrenčić, Marijana ; Radišić Biljak, Vanja ; Božičević, Sandra ; Prašek, Manja ; Pavković, Pajica ; Knotek, Mladen

Izvornik
Clinical biochemistry (0009-9120) 45 (2012), 18; 1694-1696

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, kratko priopcenje, znanstveni

Ključne riječi
diabetes; microalbuminuria; eGFR; MDRD; CKD-EPI

Sažetak
The aim of this study was to compare the preformance of Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease Study (MDRD) equation in estimating GFR in a large cohort of diabetic patients with various degrees of albuminuria. In a group of 842 diabetic patients GFR was estimated from standardized creatinine, with MDRD-Study and CKD-EPI equations, and their performance evaluated regarding clinical stages of albuminuria and chronic kidney disease (CKD). Patients with normoalbuminuria had higher eGFR when calculated by CKD-EPI, than MDRD-Study equation [median (IQR): 103 (91-115) vs 97 (85- 113) mL/min/1.73 m2, p=0.006, n=364], which significantly influenced the prevalence of stage 1 CKD [eGFR>90 mL/min/1.73 m2: 76, 7% (CKD-EPI) vs. 65, 1% (MDRD-Study), P=0, 005]. There were no differences between the eGFR values derived by two equations in patients with micro-and macroalbuminuria, and more advanced staging of CKD. CKD-EPI equation might be a superior surrogate marker of GFR in patients with normoalbuminuria and hyperfiltration and could be used as a screening tool for early renal impairment in diabetes. It's validity as a marker of progression of diabetic nephropathy merits further investigation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
044-0000000-3356 - Imunološki nadzor u bolesnika s transplantiranim solidnim organom (Knotek, Mladen, MZOS ) ( POIROT)
045-1191348-0139 - Biomolekule guanidinskog tipa u šećernoj bolesti (Vučić Lovrenčić, Marijana, MZOS ) ( POIROT)

Ustanove:
Klinička bolnica "Merkur",
Klinika za dijabetes, endokrinologiju i bolesti metabolizma Vuk Vrhovac

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com ac.els-cdn.com dx.doi.org

Citiraj ovu publikaciju:

Vučić Lovrenčić, Marijana; Radišić Biljak, Vanja; Božičević, Sandra; Prašek, Manja; Pavković, Pajica; Knotek, Mladen
Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria // Clinical biochemistry, 45 (2012), 18; 1694-1696 doi:10.1016/j.clinbiochem.2012.07.115 (međunarodna recenzija, kratko priopcenje, znanstveni)
Vučić Lovrenčić, M., Radišić Biljak, V., Božičević, S., Prašek, M., Pavković, P. & Knotek, M. (2012) Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria. Clinical biochemistry, 45 (18), 1694-1696 doi:10.1016/j.clinbiochem.2012.07.115.
@article{article, year = {2012}, pages = {1694-1696}, DOI = {10.1016/j.clinbiochem.2012.07.115}, keywords = {diabetes, microalbuminuria, eGFR, MDRD, CKD-EPI}, journal = {Clinical biochemistry}, doi = {10.1016/j.clinbiochem.2012.07.115}, volume = {45}, number = {18}, issn = {0009-9120}, title = {Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria}, keyword = {diabetes, microalbuminuria, eGFR, MDRD, CKD-EPI} }
@article{article, year = {2012}, pages = {1694-1696}, DOI = {10.1016/j.clinbiochem.2012.07.115}, keywords = {diabetes, microalbuminuria, eGFR, MDRD, CKD-EPI}, journal = {Clinical biochemistry}, doi = {10.1016/j.clinbiochem.2012.07.115}, volume = {45}, number = {18}, issn = {0009-9120}, title = {Estimating glomerular filtration rate (GFR) in diabetes : The performance of MDRD and CKD-EPI equations in patients with various degrees of albuminuria}, keyword = {diabetes, microalbuminuria, eGFR, MDRD, CKD-EPI} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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