hrvatski

Carotid intima-media thickness in patients with chronic and aggressive periodontitis

Objective: The objective of this study was to investigate the relationship between carotid intima-media thickness (IMT) and periodontal status in periodontitis patients. Materials and methods: The study was conducted on 128 subjects divided into four groups. The test groups consisted of 37 patients with chronic periodontitis (18 men and 19 women, mean age 57, 2±8, 0 years) and 30 patients with aggressive periodontitis (13 men and 17 women, mean age 34, 7±6, 3 years). There were 27 subjects in the control group for chronic periodontitis (11 men and 16 women, mean age 53, 0±10, 1 years), and 34 subjects in the control group for aggressive periodontitis (15 men and 19 women, mean age 27, 7±5, 7 years). Both control groups consisted of periodontally healthy volunteers. Periodontal condition was assessed using periodontal indices. Triglycerides, HDL cholesterol, LDL cholesterol, total serum cholesterol, high sensitive C-reactive protein (hsCRP), and glucose levels were quantified in serum. IMT measurements on common carotid artery were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results: This research revealed significantly higher values of overall (0, 8 mm) and right (0, 8 mm) carotid IMT in chronic periodontitis patients only. Chronic periodontitis was statistically significant predictor (p=0, 003) for the right carotid IMT in the multivariate model, when potential confounding factors were included. Both periodontitis groups mainly included nonsmokers, and had statistically higher levels of hsCRP (2, 2 and 1, 4 mg/L). Conclusions: The study demonstrated that chronic periodontitis can be linked with carotid atherosclerosis, but further research is required to more precisely assess the influence of aggressive periodontitis on carotid IMT.

Chronic Periodontitis ; Aggressive Periodontitis ; Carotid stenosis ; Atherosclerosis ; Carotid Intima-Media Thickness

nije evidentirano

engleski

Carotid intima-media thickness in patients with chronic and aggressive periodontitis

Objective: The objective of this study was to investigate the relationship between carotid intima-media thickness (IMT) and periodontal status in periodontitis patients. Materials and methods: The study was conducted on 128 subjects divided into four groups. The test groups consisted of 37 patients with chronic periodontitis (18 men and 19 women, mean age 57, 2±8, 0 years) and 30 patients with aggressive periodontitis (13 men and 17 women, mean age 34, 7±6, 3 years). There were 27 subjects in the control group for chronic periodontitis (11 men and 16 women, mean age 53, 0±10, 1 years), and 34 subjects in the control group for aggressive periodontitis (15 men and 19 women, mean age 27, 7±5, 7 years). Both control groups consisted of periodontally healthy volunteers. Periodontal condition was assessed using periodontal indices. Triglycerides, HDL cholesterol, LDL cholesterol, total serum cholesterol, high sensitive C-reactive protein (hsCRP), and glucose levels were quantified in serum. IMT measurements on common carotid artery were performed using Aloka ProSound ALPHA 10 with 13 MHz linear probe. Results: This research revealed significantly higher values of overall (0, 8 mm) and right (0, 8 mm) carotid IMT in chronic periodontitis patients only. Chronic periodontitis was statistically significant predictor (p=0, 003) for the right carotid IMT in the multivariate model, when potential confounding factors were included. Both periodontitis groups mainly included nonsmokers, and had statistically higher levels of hsCRP (2, 2 and 1, 4 mg/L). Conclusions: The study demonstrated that chronic periodontitis can be linked with carotid atherosclerosis, but further research is required to more precisely assess the influence of aggressive periodontitis on carotid IMT.

Chronic Periodontitis ; Aggressive Periodontitis ; Carotid stenosis ; Atherosclerosis ; Carotid Intima-Media Thickness

nije evidentirano