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Pregled bibliografske jedinice broj: 605296

Analogues of 1, 3-bis(4-nitrophenyl)triazenes, their pharmaceutically acceptable salts and N-acyl derivatives for tumour treatment


Osmak, Maja; Slovenko, Polanc, Čimbora-Zovko, Tamara; Brozović, Anamaria; Kočevar, Marjan; Majce, Vita; Alić, Branko
Analogues of 1, 3-bis(4-nitrophenyl)triazenes, their pharmaceutically acceptable salts and N-acyl derivatives for tumour treatment
(2012)


Naslov
Analogues of 1, 3-bis(4-nitrophenyl)triazenes, their pharmaceutically acceptable salts and N-acyl derivatives for tumour treatment

Autori
Osmak, Maja ; Slovenko, Polanc, Čimbora-Zovko, Tamara ; Brozović, Anamaria ; Kočevar, Marjan ; Majce, Vita ; Alić, Branko

Broj patenta
US 8, 217, 022 B2

Godina
2012

Datum patenta
10.07.2012.

Sažetak
The present patent gives the 1, 3-bis(4-nitrophenyl)triazenes, their farmaceutically acceptable salts and N-acyl derivatives that inbibit the cell division ; they could be potentially used for cancer treatment. The selected representatives from this new group of compounds are highly cytotoxic to tumor cells and their drug-resistant subline, but less cytotoxic to normal cells.

Izvorni jezik
Engleski

Znanstvena područja
Biologija



POVEZANOST RADA


Projekt / tema
098-0982913-2748 - Stanični odgovor na citotoksične spojeve i razvoj otpornosti (Maja Osmak, )

Ustanove
Institut "Ruđer Bošković", Zagreb