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Genetic Substructuring of the populations from the area of South-Eastern Europe


Novokmet, Natalija; Marjanović, Damir; Škaro, Vedrana; Projić, Petar; Lauc, Gordan; Grahovac, Blaženka; Kapović, Miljenko; Vidovič, Maruška; Rudan, Pavao
Genetic Substructuring of the populations from the area of South-Eastern Europe // Promotion of Anthropological Science. Biological - Medical Anthropology - Anthropology of Future / Vidovič, Maruška (ur.).
Ljubljana: National institute of public health, 2013. str. 27-27 (poster, međunarodna recenzija, sažetak, znanstveni)


Naslov
Genetic Substructuring of the populations from the area of South-Eastern Europe

Autori
Novokmet, Natalija ; Marjanović, Damir ; Škaro, Vedrana ; Projić, Petar ; Lauc, Gordan ; Grahovac, Blaženka ; Kapović, Miljenko ; Vidovič, Maruška ; Rudan, Pavao

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Promotion of Anthropological Science. Biological - Medical Anthropology - Anthropology of Future / Vidovič, Maruška - Ljubljana : National institute of public health, 2013, 27-27

ISBN
978-961-6911-17-7

Skup
5th Slovenian Congress on Preventive Medicine

Mjesto i datum
Portorož, Slovenia, 15-17.11. 2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
SE European populations; Croatian islands; microsatellite; human population differentiation analyses; STRUCTURE

Sažetak
Despite of an overall low differentiation in human population, especially in Europe area, varial local factors such as geographic, cultural or continuing reproductive isolation can enhance genetic discontinuity. As some of the few persisting isolates among contemporary South- Eastern European (SE European) human groups, isolated Croatian islands are among the most suitable models for analyses of human population differentiation. In this study the data obtained by means of the analysis of 9 autosomal STR loci of microsatelite DNA in Croatian islands and Slovenian populations were integrated with the published data from other Croatian islands and wide SE European region. The sample was defined hierarchically in two levels: the first one included 7 Croatian islands sub-populations and the second one included 10 neighboring SE European populations. We detected lower genetic differentiation at the higher lever of grouping of SE European populations (K = 3) than at the level of sub-populations of Croatia islands (K = 6). Results obtained with the clustering algorithm implemented by STRUCTURE illustrate that a relatively small number of loci is sufficient to reveal consistent structure when differentiation is high. These findings are supportive of the notion that specific genetic features of isolated Croatian islands have been shaped through the constant interaction of population genetic characteristic and wide spectrum of environmental influences through history. Due to strong influence of genetic drift, small isolates rapidly acquire very distinctive alleles frequencies.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Etnologija i antropologija



POVEZANOST RADA


Projekt / tema
062-19627660309
196-1962766-2751 - Populacijska struktura Hrvatske - antropogenetički pristup (Pavao Rudan, )
309-1300855-2738 - Razvoj sustava za DNA analizu arheoloških koštanih uzoraka (Damir Marjanović, )

Ustanove
Medicinski fakultet, Rijeka,
Institut za antropologiju,
GENOS d.o.o.