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Pregled bibliografske jedinice broj: 599877

How simple can a model of an empty viral capsid be? Charge distributions in viral capsids


Lošdorfer Božič, Anže; Šiber, Antonio; Podgornik, Rudi
How simple can a model of an empty viral capsid be? Charge distributions in viral capsids // JOURNAL OF BIOLOGICAL PHYSICS, 38 (2012), 4; 657-671 doi:10.1007/s10867-012-9278-4 (međunarodna recenzija, članak, znanstveni)


Naslov
How simple can a model of an empty viral capsid be? Charge distributions in viral capsids

Autori
Lošdorfer Božič, Anže ; Šiber, Antonio ; Podgornik, Rudi

Izvornik
JOURNAL OF BIOLOGICAL PHYSICS (0092-0606) 38 (2012), 4; 657-671

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Virus; charge; electrostatics; capsid; protein

Sažetak
We investigate and quantify salient features of the charge distributions on viral capsids. Our analysis combines the experimentally determined capsid geometry with simple models for ionization of amino acids, thus yielding a detailed description of spatial distribution for positive and negative charges across the capsid wall. The obtained data is processed in order to extract the mean radii of distributions, surface charge densities, as well as dipole moment densities. The results are evaluated and examined in light of previously proposed models of capsid charge distributions, which are shown to have to some extent limited value when applied to real viruses.

Izvorni jezik
Engleski

Znanstvena područja
Fizika



POVEZANOST RADA


Projekt / tema
035-0352828-2837 - Energetskom kompeticijom uvjetovani oblici i strukture nanometarskih sustava (Antonio Šiber, )

Ustanove
Institut za fiziku, Zagreb

Autor s matičnim brojem:
Antonio Šiber, (226073)

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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