Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 599047

Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares


Radeljak, A; Podobnik Brlečić, P; Ožvald, I; Gebauer Vuković, B; Podobnik, M; Stojanović, N.
Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares // Biochemia Medica 2012 ; 22(3):267-402 ; A17-A204 / Šimundić, AM (ur.).
Zagreb: HDMBLM, 2012. str. A181-A182 (poster, međunarodna recenzija, sažetak, stručni)


CROSBI ID: 599047 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares

Autori
Radeljak, A ; Podobnik Brlečić, P ; Ožvald, I ; Gebauer Vuković, B ; Podobnik, M ; Stojanović, N.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Biochemia Medica 2012 ; 22(3):267-402 ; A17-A204 / Šimundić, AM - Zagreb : HDMBLM, 2012, A181-A182

Skup
2nd European Joint Congress of European Federatioin of Clinical Chemistry and laboratory Medicine (EFCC) and European Union of Medical Specialists (UEMS)/ 7th Congrerss of Croatian Society of Medical Biochemistry and Laboratory Medicine (CSMBLM)

Mjesto i datum
Dubrovnik, Hrvatska, 10.-13.10.2012

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Down syndrom ; screening softwares

Sažetak
Background. First trimetser screening by a combination of maternal age, fetal nuchal translucency and maternal serum free-b-hCG and PAPP-A can identify about 85-90% of fetuses with trisomy 21 and other mayor aneuploidies. The aim of this study was to compare risk calculations performed using two different softwares. materials and methods. PAPP-A and free-b-hCG concentrations were measured by electrochemiluminescent immunoassay /ECL) on Roche Elecsys analyzer. The obtained results were within the target values of internal and external quality assurance programme (UKNEQAS scheme for First Trimester Downs Syndrome Screening). Nuchal translucency was measured by sonographers with FMF Certificate of Competence. Risk calculations were performed using "SsdwLab 5.0.9" (Roche, certified by FMF) and "Fetal Medicine Foundation" softwares. Results. Patients (N=247) were devided into high, intermediate and low risk groups. The obtained distributions per group were: high risk 18 (7, 29%), intermediate risk 36 (14, 57%) and low risk 193(78, 14%)patients using SsdwLab 5.0.9 software vs. high risk 12 (4, 86%), intermediate risk 26 (10, 53%) and low risk 209 (84, 61%) patients using FMF software. 18 patients were classified as high risk by SsdwLab 5.0.9 vs. 10 (55, 6%) as high risk and 8 (44, 4%)as intermediate risk using FMF software. Only one fetus from the high risk group (by both softwares) was trisomy 21 positive, which was confirmed by amniocentesis. Conclusions. Comparing risk calculations performed using "SsdwLab 5.0.9" and "Fetal Medicine Foundation" softwares, we concluded that SSdwLab 5.0.9 calculates higher risk for the same input parameters. Further research will be aimed at discovering the causes of observed differences.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Profili:

Avatar Url Mario Podobnik (autor)

Avatar Url Nataša Stojanović (autor)

Avatar Url Beata Gebauer (autor)

Avatar Url Ivan Ožvald (autor)


Citiraj ovu publikaciju:

Radeljak, A; Podobnik Brlečić, P; Ožvald, I; Gebauer Vuković, B; Podobnik, M; Stojanović, N.
Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares // Biochemia Medica 2012 ; 22(3):267-402 ; A17-A204 / Šimundić, AM (ur.).
Zagreb: HDMBLM, 2012. str. A181-A182 (poster, međunarodna recenzija, sažetak, stručni)
Radeljak, A., Podobnik Brlečić, P., Ožvald, I., Gebauer Vuković, B., Podobnik, M. & Stojanović, N. (2012) Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares. U: Šimundić, A. (ur.)Biochemia Medica 2012 ; 22(3):267-402 ; A17-A204.
@article{article, editor = {\v{S}imundi\'{c}, A.}, year = {2012}, pages = {A181-A182}, keywords = {Down syndrom, screening softwares}, title = {Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares}, keyword = {Down syndrom, screening softwares}, publisher = {HDMBLM}, publisherplace = {Dubrovnik, Hrvatska} }
@article{article, editor = {\v{S}imundi\'{c}, A.}, year = {2012}, pages = {A181-A182}, keywords = {Down syndrom, screening softwares}, title = {Comparison of the "Ssdwlab 5.0.9" and "Fetal Medicine Foundation" Down syndrom screening softwares}, keyword = {Down syndrom, screening softwares}, publisher = {HDMBLM}, publisherplace = {Dubrovnik, Hrvatska} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





Contrast
Increase Font
Decrease Font
Dyslexic Font