engleski

An amitaz intoxication in Croatian warmblood horse: case report

Amitraz (formamidine) is a veterinary and agricultural pharmaceutical drug that is used worldwide as an acaricide and insecticide in many species but it is not approved for horses. In mammals amitraz has a highly complex pharmacological activity that can be related to stimulation of alfa-2 adrenergic receptors. A three year old male croatian warmblood was admitted at the clinic with a history of of an acute abdominal pain, depression and mild ataxia in the last 24 hours. He was sprayed with an amitraz product (Taktic®, 12, 5%, Intervet) two days previous to referral. Physical examination revealed depression, moderate dehydration, poor gut motility, normal peritoneal fluid and ingesta filled, firm pelvic flexure. A complete hemathology and serum biochemistry blood profile showed no specific changes. The horse was thoroughly washed with a chlorhexidine soap and treated symptomatically with IV polyionic crystalloid fluids, metamizol, flunixine meglumine and mulitple doses of mineral oil and water per os. The following day the horse already showed improved gut motility and softer pelvic flexure on rectal palpation. On day three, gut motility returned to normal, rectal palpation of pelvic flecture showed no abnormality, and there were no signs of ataxia and depression. The use of alfa-2 adrenergic anatgonists and yohimbin for treatment amitraz intoxication is described in the literature, but in this case patient recovered fully within 3 days only with medical therapy for colonic impation after the initial wash.

acute abdominal pain; depression; insecticide spray for horses; mild ataxia; recovery

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