Performance of the StatStrip POCT analyzer in detecting hypoglycaemic episodes in diabetic patients (CROSBI ID 590739)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Vučić Lovrenčić, Marijana ; Radišić Biljak, Vanja ; Božičević, Sandra ; Car, Nikica
engleski
Performance of the StatStrip POCT analyzer in detecting hypoglycaemic episodes in diabetic patients
Background: Improving glycaemic control, whilst minimizing risk of hypoglycaemia is the ultimate goal of diabetes management. Intensified insulin treatment is the most common source of iatrogenic hypoglycaemia. Due to the hypoglycaemia unawareness, common in diabetes, many of the hypoglycaemic episodes remain undiagnosed and untreated, leading to a variety of adverse outcomes, ranging from mild autonomic symptoms to death. Accurate and readily available plasma glucose monitoring is of utmost importance in diagnosis and subsequent treatment of hypoglycaemia. The aim of this study was to evaluate the performance of a new type glucose sensor for the POCT glucose analyzer (StatStrip, Nova Biomedical, USA) in detecting hypoglycaemic episodes in diabetic patients upon institution of intensified insulin treatment. Materials and methods: Capillary plasma glucose was measured by the StatStrip POCT glucose analyzer in hospitalized diabetic patients (N = 49) upon institution of intensified insulin treatment (glycaemic profile: 8 times per 24 hours) and results were compared to the reference hexokinase procedure (Olympus AU400, Beckman Coulter, USA). Results: A total of 41 hypoglycaemic episodes (plasma glucose ≤ 3.9 mmol/L) were detected in the study period. There was no statistically significant bias between plasma glucose, as measured by the StatStrip and reference procedure (3.0 ± 0.83 vs. 3.1 ± 0.69 mmol/L, P = 0.071). Diagnostic test revealed a 95.1% sensitivity of the StatStrip in detecting hypoglycaemia, when tested against reference procedure. Conclusions: The StatStrip POCT glucose analyzer showed excellent performance and clinical accuracy for detecting hypoglycaemic episodes in diabetic patients treated with intensified insulin therapy.
Hypoglycaemia; diabetes; StatStrip; POCT
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Podaci o prilogu
A84-A84.
2012.
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objavljeno
Podaci o matičnoj publikaciji
Biochemia medica
Šimundić, Ana-Maria
Zagreb: Hrvatsko društvo za medicinsku biokemiju i laboratorijsku medicinu (HDMBLM)
1330-0962
Podaci o skupu
2nd European Joint Congress of EFLM and UEMS and 7th Congress of the Croatian Society for Medical Biochemistry and Laboratory medicine (CSMBLM): Laboratory Medicine at the Clinical Interface
poster
01.01.2012-01.01.2012
Dubrovnik, Hrvatska
Povezanost rada
Kliničke medicinske znanosti