engleski

Nutritional Status In Children With High-Risk Brain Tumor–Diagnostic And Therapeutic Possibilities

Purpose: High risk CNS tumors requires intensive oncological treatment (surgery, radiotherapy, megaterapy). Illness and intensive care are often brings the child into a state of malnutrition. With the increased laboratory monitoring, treatment involves intensive supportive therapy. Methods: In this study we analyzed 30 children with a diagnosis of high-risk malignant CNS tumors. We have monitored changes in body weight and body mass index during the implementation of treatment. Applied supportive nutritional therapy, we followed an intensive laboratory monitoring of glucose and acid-base status. Furthermore, monitoring electrolyte (phosphate, potassium, magnesium, calcium) has been made in terms of possible development of the refeeding syndrome. Laboratory monitoring also included the determination of proteins (total proteins, albumin) and metabolites (urea, creatinine). Data were compared with the outcome of the disease. Results: In the group of children with depletion of body weight, body mass index and evidence changes in laboratory values (phosphate, potassium, magnesium, calcium) has been registered worse outcome of disease. In patients with small changes in the body weight and the body mass index and appropriate laboratory findings we found better outcome of disease. Conclusion: Based on the results we confirm the necessity of a careful approach to the children with high-risk brain tumors in terms of overall nutritional status. We are thinking about the need for careful energy recovery and time correction of electrolyte imbalance in a case of development of refeeding syndromes. The goal is to increase body mass and better outcome of disease.

brain tumors; malnutrition; refeeding syndrome; electrolyte imbalance

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