engleski

Synthesis and Antioxidant Evaluati on of Schiff Bases Derived from 2, 6-Pyridinedicarboxylic Acid

A series of novel Schiff bases derived from dipicolinic acid was synthesized and evaluated for antioxidant and iron chelating activity. In most cases Schiff bases derived from di-hydrazide showed higher antioxidant activity than the ones derived from mono-hydrazide and some of them are very promising considering the fact of being better antioxidants than the standards used in the investigation. For iron chelating activity substituents had a greater impact on the activity than mono or di-hydrazide skeleton.

antioxidant; dipicolinic acid; metal chelating; Schiff base

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