Serum CA-125 tumor marker in endometrial adenocarcinoma. (CROSBI ID 186537)
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Podaci o odgovornosti
Kukura, Vlastimir ; Zovko, Gojko ; Ciglar, Srećko ; Markulin-Grgić, Lijerka ; Šantek, Fedor ; Podgajski, Mario ; Duić, Željko
engleski
Serum CA-125 tumor marker in endometrial adenocarcinoma.
One hundred and seventy-four patients, mean age 61.23 +/- 9.41 years old, with irregular perimenopausal haemorrhage were included in the study. Fractional curettage was performed in all patients. When the pathohistologic findings were adenocarcinoma the concentration of CA-125 tumor marker was determined. Hysterectomy with bilateral salpingo-oophorectomy was determined. In 142 cases carcinoma was restricted to the uterus and in 32 patients extrauterine metastatic disease was found. In the former group CA-125 was positive in 130 patients with a mean value of 64.12 +/- 22.41 U/ml serum. In the latter group the cancer antigen was positive in 29 patients with a mean value of 244.82 +/- 68.11 U/ml. High production is associated with increased metastatic potential.
Ca-125; endometrial cancer
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