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Pregled bibliografske jedinice broj: 594830

Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels


Strenja Linić, Ines; Šoša, Ivan; Kovačević, Miljenko; Ivančić, Aldo; Trobonjača, Zlatko; Grubešić, Aron; Štifter, Sanja
Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels // Medical hypotheses, 80 (2013), 1; 26-28 doi:10.1016/j.mehy.2012.09.022 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 594830 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels

Autori
Strenja Linić, Ines ; Šoša, Ivan ; Kovačević, Miljenko ; Ivančić, Aldo ; Trobonjača, Zlatko ; Grubešić, Aron ; Štifter, Sanja

Izvornik
Medical hypotheses (0306-9877) 80 (2013), 1; 26-28

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
MCP-1; atherosclerosis; re-stenosis

Sažetak
As cardiovascular pathology grows in numbers, research into the discovery of new chemokine biomarkers should not be neglected, as they seem to be paramount in atherosclerosis prevention and its early detection. Chemokines attract and activate leukocytes and are well recognized in the environment of inflammatory response. MCP-1 is a valuable chemokine whose potential to become a new crucial atherosclerosis marker is surely worth investigating. Since quantities of MCP-1 found in lesions are as low as immeasurable, we propose the use of an imunohistochemical method for the quantification of MCP-1 levels in atherosclerotic lesions. Additionally, serum levels of MCP-1 can be measured by commercially available immunoassays. Proposed MCP-1 concentration increase may explain the acceleration in lesion’s atherosclerosis progression as chemokine activation occurs once they bind to specific ligands. If proven, this hypothesis would indicate the need for further studies in order to objectively link the increased MCP-1 expression with carotid re-stenosis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
062-0000000-3544 - Antigen predočne stanice u jetri miša tijekom citomegalovirusne infekcije (Trobonjača, Zlatko, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com ac.els-cdn.com dx.doi.org

Citiraj ovu publikaciju:

Strenja Linić, Ines; Šoša, Ivan; Kovačević, Miljenko; Ivančić, Aldo; Trobonjača, Zlatko; Grubešić, Aron; Štifter, Sanja
Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels // Medical hypotheses, 80 (2013), 1; 26-28 doi:10.1016/j.mehy.2012.09.022 (međunarodna recenzija, članak, znanstveni)
Strenja Linić, I., Šoša, I., Kovačević, M., Ivančić, A., Trobonjača, Z., Grubešić, A. & Štifter, S. (2013) Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels. Medical hypotheses, 80 (1), 26-28 doi:10.1016/j.mehy.2012.09.022.
@article{article, author = {Strenja Lini\'{c}, Ines and \v{S}o\v{s}a, Ivan and Kova\v{c}evi\'{c}, Miljenko and Ivan\v{c}i\'{c}, Aldo and Trobonja\v{c}a, Zlatko and Grube\v{s}i\'{c}, Aron and \v{S}tifter, Sanja}, year = {2013}, pages = {26-28}, DOI = {10.1016/j.mehy.2012.09.022}, keywords = {MCP-1, atherosclerosis, re-stenosis}, journal = {Medical hypotheses}, doi = {10.1016/j.mehy.2012.09.022}, volume = {80}, number = {1}, issn = {0306-9877}, title = {Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels}, keyword = {MCP-1, atherosclerosis, re-stenosis} }
@article{article, author = {Strenja Lini\'{c}, Ines and \v{S}o\v{s}a, Ivan and Kova\v{c}evi\'{c}, Miljenko and Ivan\v{c}i\'{c}, Aldo and Trobonja\v{c}a, Zlatko and Grube\v{s}i\'{c}, Aron and \v{S}tifter, Sanja}, year = {2013}, pages = {26-28}, DOI = {10.1016/j.mehy.2012.09.022}, keywords = {MCP-1, atherosclerosis, re-stenosis}, journal = {Medical hypotheses}, doi = {10.1016/j.mehy.2012.09.022}, volume = {80}, number = {1}, issn = {0306-9877}, title = {Predicting Carotid Restenosis by Comparison of Plaque MCP-1 mRNA Expression and Serum Levels}, keyword = {MCP-1, atherosclerosis, re-stenosis} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





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