Gizzerosine Induced Histoopathological Lesions in Broiler Chicks (CROSBI ID 478257)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Tišljar, Marina ; Grabarević, Željko ; Artuković, Branka ; Šimec, Zoran ; Džaja, Petar ; Herak-Perković, Vlasta
engleski
Gizzerosine Induced Histoopathological Lesions in Broiler Chicks
Gizzerosine is a well-known toxic substance spontaneously produced during the heating process of fish meal. Because of its action on H2-receptors of histamine it stimulates gastric juice secretion and induces gizzard erosions (GE) (Okazaki et al., 1983; Masumura et al., 1985). Its pathological effects on other organs have not yet been described. In this work the pathological effects of gizzerosine on different chicken organs were investigated. The ROSS broiler chicks were divided into three groups: group A received 100% of non-medicated commercial mash for broiler chicks. For group B 50% of commercial mash was replaced with unheated fish meal (0.5 ppm gizzerosine) and in group C with heated fish meal (1.15 ppm gizzerosine) during an experimental 7-day period. Fourteen chicks from each group were sacrificed every day during one week. Necropsy did not reveal notable differences between treated groups. Samples of gastrointestinal, cardiovascular and lymphoid organs, of brain and kidney were collected for histopathological analysis; fixed in 10% formalin solution, embedded in paraffin, sections of 5 ?m thickness were cut on a microtome and stained with hematoxilyn-eosin stain. Histopathological findings predominantly developed in gastrointestinal organs (proventricular mucosal degeneration; intestinal mucosal and submucosal edema with/without multiple vacuoles; proventricular and intestinal submucosal fibroplasia; gizzard cuticle erosions). The most prominent were intestinal lesions; their severity increased towards the end of the trial, especially in group C. References Okazaki et al ., 1983; Agric. Biol. Chem. 47: 2949. Masumura et al., 1985; Poult. Sci. 64: 356
gizzerosine; broiler chicks
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Podaci o prilogu
57-x.
1999.
objavljeno
Podaci o matičnoj publikaciji
10th "Ljudevit Jurak" International Symposium on comparative Pathology
Talan-Hranilović, Jasna ; Krušlin, Božo
Zagreb:
Podaci o skupu
10th "Ljudevit Jurak" International Symposium on Comparative Pathology
predavanje
04.06.1999-05.06.1999
Zagreb, Hrvatska