Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure (CROSBI ID 185778)
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Podaci o odgovornosti
Rehm, Thomas H. ; Radić Stojković, Marijana ; Rehm, Stefanie ; Škugor, Marko ; Piantanida, Ivo ; Würthner, Frank
engleski
Interaction of Spermine-Alanine Functionalized Perylene Bisimide Dye Aggregates with ds-DNA/RNA Secondary Structure
We report for the first time on the interaction of self-assembled PBI dye aggregates with polynucleotides, revealing very high (nM) binding constants and exceptional thermal stabilization of double-stranded (ds)-DNA/RNA. Induced CD profiles of PBI dimer aggregates formed within DNA/RNA grooves show high sensitivity on the steric properties of the binding site, suggesting the applicability of such self-adjusting excitonically coupled PBI dimers for the sensing of the DNA/RNA secondary structure.
perylene bisimide; aggregates; DNA; RNA; CD spectropolyrimetry
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