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Pregled bibliografske jedinice broj: 589937

Reference intervals for reproductive hormones in prepubertal children on the automated Roche cobas e 411 analyzer


Zec, Ivana; Kučak, Ivana; Begčević, Ilijana; Šimundić, Ana-Maria; Tišlarić-Medenjak, Dubravka; Bukovec Megla, Željka; Vrkić, Nada
Reference intervals for reproductive hormones in prepubertal children on the automated Roche cobas e 411 analyzer // Clinical biochemistry, 45 (2012), 15; 1206-1212 doi:10.1016/j.clinbiochem.2012.05.019 (međunarodna recenzija, članak, znanstveni)


Naslov
Reference intervals for reproductive hormones in prepubertal children on the automated Roche cobas e 411 analyzer

Autori
Zec, Ivana ; Kučak, Ivana ; Begčević, Ilijana ; Šimundić, Ana-Maria ; Tišlarić-Medenjak, Dubravka ; Bukovec Megla, Željka ; Vrkić, Nada

Izvornik
Clinical biochemistry (0009-9120) 45 (2012), 15; 1206-1212

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Reference intervals; reproductive hormones; prepubertal children; Roche analyzer

Sažetak
Objectives were to establish reference intervals for luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), progesterone (P), total and free testosterone (T) and sex-hormone binding globulin (SHBG) in prepubertal children and to assess age- and gender-related differences. A total of 948 subjects, 480 girls and 468 boys, between 1 and 11 years of age, were included in this study. All assays were performed on a Roche cobas e 411 immunoassay analyzer. Reference intervals have been evaluated according to the most recent CLSI guidelines. Median values of LH, FSH and T were significantly higher in subgroups ranging from ≥8 to <11 years, for both genders. In girls of that age, reference values of E2 were significantly higher than in younger ones, and in boys of the corresponding age. Established reference intervals are applicable to other laboratories that use the same instrumentation.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Farmacija



POVEZANOST RADA


Projekt / tema
134-0061245-0205 - Hemoreološki poremećaji u kroničnim bolestima (Nada Vrkić, )
134-1340227-0200 - Upala i udio farmakogenetike u razvoju i ishodu akutnih i kroničnih bolesti (Ana-Maria Šimundić, )

Ustanove
Farmaceutsko-biokemijski fakultet, Zagreb,
KBC "Sestre Milosrdnice"

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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