Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 588604

Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit


Matanović-Škugor, Maja; Štimac, Vlado; Palej, Ivana; Lugarić, Đurđica; Čipčić Paljetak, Hana; Filić, Darko; Modrić, Marina; Đilović, Ivica; Gembarovski, Dubravka; Mutak, Stjepan et al.
Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit // Bioorganic & medicinal chemistry, 18 (2010), 17; 6547-6558 doi:10.1016/j.bmc.2010.06.050 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 588604 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit

Autori
Matanović-Škugor, Maja ; Štimac, Vlado ; Palej, Ivana ; Lugarić, Đurđica ; Čipčić Paljetak, Hana ; Filić, Darko ; Modrić, Marina ; Đilović, Ivica ; Gembarovski, Dubravka ; Mutak, Stjepan ; Eraković Haber, Vesna ; Holmes, David J. ; Ivezić-Schoenfeldd, Zrinka ; Alihodžić, Sulejman

Izvornik
Bioorganic & medicinal chemistry (0968-0896) 18 (2010), 17; 6547-6558

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
macrolide ; quinolone ; antibacterial activity ; resistance

Sažetak
The synthesis and antimicrobial activity of a new class of macrolide antibiotics which consist of a macrolide scaffold and a quionolone unit covalently connected by an appropriate linker are described. Optimization of several synthetic steps and structural properties of lead compound 26 are discussed. Promising antibacterial properties of this compound and some of its analogues are reported.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Ustanove:
Pliva-Istraživački institut,
Prirodoslovno-matematički fakultet, Zagreb,
Fidelta d.o.o.

Citiraj ovu publikaciju

Matanović-Škugor, Maja; Štimac, Vlado; Palej, Ivana; Lugarić, Đurđica; Čipčić Paljetak, Hana; Filić, Darko; Modrić, Marina; Đilović, Ivica; Gembarovski, Dubravka; Mutak, Stjepan et al.
Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit // Bioorganic & medicinal chemistry, 18 (2010), 17; 6547-6558 doi:10.1016/j.bmc.2010.06.050 (međunarodna recenzija, članak, znanstveni)
Matanović-Škugor, M., Štimac, V., Palej, I., Lugarić, Đ., Čipčić Paljetak, H., Filić, D., Modrić, M., Đilović, I., Gembarovski, D. & Mutak, S. (2010) Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit. Bioorganic & medicinal chemistry, 18 (17), 6547-6558 doi:10.1016/j.bmc.2010.06.050.
@article{article, year = {2010}, pages = {6547-6558}, DOI = {10.1016/j.bmc.2010.06.050}, keywords = {macrolide, quinolone, antibacterial activity, resistance}, journal = {Bioorganic and medicinal chemistry}, doi = {10.1016/j.bmc.2010.06.050}, volume = {18}, number = {17}, issn = {0968-0896}, title = {Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit}, keyword = {macrolide, quinolone, antibacterial activity, resistance} }
@article{article, year = {2010}, pages = {6547-6558}, DOI = {10.1016/j.bmc.2010.06.050}, keywords = {macrolide, quinolone, antibacterial activity, resistance}, journal = {Bioorganic and medicinal chemistry}, doi = {10.1016/j.bmc.2010.06.050}, volume = {18}, number = {17}, issn = {0968-0896}, title = {Synthesis and biological activity of 4''-O-Acyl Derivatives of 14- and 15-membered Macrolides Linked to omega-Quinolone-carboxylic Unit}, keyword = {macrolide, quinolone, antibacterial activity, resistance} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font