engleski

Characterization of electrospun 3D nanofiber scaffolds for tissue engineering

Electrospun nano/micro porous materials have shown the advantage of usage in the field of tissue engineering as being the perfect candidate for mimicking the natural structure of the living tissues. For an optimal 3D nanofiber scaffold design morphology and mechanical behaviour evaluation of the structure is crucial. Within this respect the study describes the change of the fiber diameter and pore area with the polymer solution concentration and the volume flow rate, thus the influence of the total structure porosity on the stress-strain behaviour of the electrospun PU material. Three concentration of the polyurethane dissolved in dual solvent system were successfully electrospun into nonwoven 3D materials. SEM analysis of the electrospun structures showed that more viscous polymer solution results in thicker fibers and wider top pores opening between the fibers and finally lower total porosity. Higher breaking force increased the elongation of the electrospun material with the lowest porosity of ~74%, at highest solution concentration and higher volume flow rate.

electrospun ; PU ; morphology ; stress-strain behaviour

nije evidentirano