Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 583964

Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome


Čubranić, Zlatko; Madžar, Željko; Matijević, Sanja; Dvornik, Štefica; Fišić, Elizabeta; Tomulić, Vjekoslav; Kunišek, Juraj; Laškarin, Gordana; Kardum, Igor; Zaputović, Luka
Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome // Biochemia Medica, 22 (2012), 2; 225-236 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 583964 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome

Autori
Čubranić, Zlatko ; Madžar, Željko ; Matijević, Sanja ; Dvornik, Štefica ; Fišić, Elizabeta ; Tomulić, Vjekoslav ; Kunišek, Juraj ; Laškarin, Gordana ; Kardum, Igor ; Zaputović, Luka

Izvornik
Biochemia Medica (1330-0962) 22 (2012), 2; 225-236

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
biological markers; heart fatty acid-binding protein; glycogen phosphorylase; sensitivity; specificity; acute myocardial infarction

Sažetak
Introduction: This study aimed to assess whether heart fatty acid-binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) could be used for the accurate diagnosis of acute myocardial infarction (AMI) in acute coronary syndrome (ACS) patients. Materials and methods: The study included 108 ACS patients admitted to a coronary unit within 3 h after chest pain onset. AMI was distinguished from unstable angina (UA) using a classical cardiac troponin I (cTnI) assay. H-FABP and GPBB were measured by ELISA on admission (0 h) and at 3, 6, 12, and 24 h after admission ; their accuracy to diagnose AMI was assessed using statistical methods. Results: From 92 patients with ACS ; 71 had AMI. H-FABP and GPBB had higher peak value after 3 h from admission than cTnI (P = 0.001). Both markers normalized at 24 h. The area under the receiver operating characteristic curves was signifi cantly greater for both markers in AMI patients than in UA patients at all time points tested, including admission (P < 0.001). At admission, the H-FABP (37%) and GPBB (40%) sensitivities were relatively low. They increased at 3 and 6 h after admission for both markers and decreased again after 24 h. It was 40% for H-FABP and approximately 2-times lower for GPBB (P < 0.01). In AMI patients, both biomarkers had similar specifi cities, positive- and negative-predictive values, positive and negative likelihood ratios, and risk ratios for AIM. Conclusion: H-FABP and GPBB can contribute to early AMI diagnosis and can distinguish AMI from UA.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Projekti:
062-0620402-0377 - Imunoregulacijske funkcije antigen predočnih stanica tijekom rane trudnoće (Laškarin, Gordana, MZOS ) ( POIROT)
062-1081875-0545 - Aterogeneza i trombogeneza u ishemijskoj bolesti srca (Zaputović, Luka, MZOS ) ( POIROT)

Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka

Citiraj ovu publikaciju:

Čubranić, Zlatko; Madžar, Željko; Matijević, Sanja; Dvornik, Štefica; Fišić, Elizabeta; Tomulić, Vjekoslav; Kunišek, Juraj; Laškarin, Gordana; Kardum, Igor; Zaputović, Luka
Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome // Biochemia Medica, 22 (2012), 2; 225-236 (međunarodna recenzija, članak, znanstveni)
Čubranić, Z., Madžar, Ž., Matijević, S., Dvornik, Š., Fišić, E., Tomulić, V., Kunišek, J., Laškarin, G., Kardum, I. & Zaputović, L. (2012) Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome. Biochemia Medica, 22 (2), 225-236.
@article{article, author = {\v{C}ubrani\'{c}, Zlatko and Mad\v{z}ar, \v{Z}eljko and Matijevi\'{c}, Sanja and Dvornik, \v{S}tefica and Fi\v{s}i\'{c}, Elizabeta and Tomuli\'{c}, Vjekoslav and Kuni\v{s}ek, Juraj and La\v{s}karin, Gordana and Kardum, Igor and Zaputovi\'{c}, Luka}, year = {2012}, pages = {225-236}, keywords = {biological markers, heart fatty acid-binding protein, glycogen phosphorylase, sensitivity, specificity, acute myocardial infarction}, journal = {Biochemia Medica}, volume = {22}, number = {2}, issn = {1330-0962}, title = {Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome}, keyword = {biological markers, heart fatty acid-binding protein, glycogen phosphorylase, sensitivity, specificity, acute myocardial infarction} }
@article{article, author = {\v{C}ubrani\'{c}, Zlatko and Mad\v{z}ar, \v{Z}eljko and Matijevi\'{c}, Sanja and Dvornik, \v{S}tefica and Fi\v{s}i\'{c}, Elizabeta and Tomuli\'{c}, Vjekoslav and Kuni\v{s}ek, Juraj and La\v{s}karin, Gordana and Kardum, Igor and Zaputovi\'{c}, Luka}, year = {2012}, pages = {225-236}, keywords = {biological markers, heart fatty acid-binding protein, glycogen phosphorylase, sensitivity, specificity, acute myocardial infarction}, journal = {Biochemia Medica}, volume = {22}, number = {2}, issn = {1330-0962}, title = {Diagnostic accuracy of heart fatty acid binding protein (H-FABP) and glycogen phosphorylase isoenzyme BB (GPBB) in diagnosis of acute myocardial infarction in patients with acute coronary syndrome}, keyword = {biological markers, heart fatty acid-binding protein, glycogen phosphorylase, sensitivity, specificity, acute myocardial infarction} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Uključenost u ostale bibliografske baze podataka::


  • CA Search (Chemical Abstracts)
  • EMBASE (Excerpta Medica)
  • Scopus, DOAJ (Directory of Open Access Journals), EBSCO/Academic Search Complete





Contrast
Increase Font
Decrease Font
Dyslexic Font