Surgical treatment of FAP (CROSBI ID 585986)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jurišić, Darko ; Held, R ; Roško, Damir ; Samardžić, Josip ; Hrečkovski, Boris ; Pitlović, Vlatka
engleski
Surgical treatment of FAP
Familial adenomatous polyposis (FAP) is a genetic autosomal dominant disorder characterized by multiple adenomatous colorectal polyps and different extracolonic manifestations (ECM), with a 100% risk of eartly colorectal cancer (CRC). FAP is associated with a deletion of chromosome 5q21, also known as the APC gene. Two major forms of heritable CRC are FAP and Lynch syndrome (hereditary nonpolyposis colorectal cancer). FAP incidence in all cases of CRC is 10-20%. Along with the risk for CRC, both syndromes are associated with elevated risk for other tumors. Endoscopic surveillance is required to detect the onset of polyposis. Ultimately, surgical treatment should be performed before the onset of cancer. In case of identified adenoma or adenocarcinoma, the procedure of choice is colectomy with mucosal proctectomy and proctocolectomy with ileal pouch- anal anastomosis (IPAA). Those procedures allow retention of rectal function. Other options are subtotal colectomy with ileonal anastomosis and total proctocolectoy with ileostomy. We present our case reports of patients with multiple adenomatous colorectal polyps treated by subtotal colectomy.
Familial adenomatous polyposis ; surgical treatment
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Podaci o prilogu
28-28.
2009.
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objavljeno
Podaci o matičnoj publikaciji
European Surgery
Lampe, Pawel
1682-8631
Podaci o skupu
2nd Central European Congress of Surgery
poster
22.04.2009-25.04.2009
Katowice, Poljska
Povezanost rada
Kliničke medicinske znanosti