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Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28)


Glasnović, Marija; Bošnjak, Ivica; Včev, Aleksandar; Soldo, Ivan; Glasnović-Horvatić, Elizabeta; Soldo-Butković, Silva; Pavela, Jasna; Mićunović, Nikola
Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28) // Collegium antropologicum, 31 (2007), 1; 345-348 (međunarodna recenzija, članak, znanstveni)


Naslov
Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28)

Autori
Glasnović, Marija ; Bošnjak, Ivica ; Včev, Aleksandar ; Soldo, Ivan ; Glasnović-Horvatić, Elizabeta ; Soldo-Butković, Silva ; Pavela, Jasna ; Mićunović, Nikola

Izvornik
Collegium antropologicum (0350-6134) 31 (2007), 1; 345-348

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
anti-citrullinated antibodies; rheumatoid arthritis; disease activity score; radiological damages

Sažetak
Determination of anti-citrullinated peptides (anti-CCP) specificity as a predictor of joint erosive changes, correlation between their serum level and radiological damages as well as disease activity score (DAS28). A trial has been conducted on a 211 patient sample fulfilling ACR criteria for rheumatoid arthritis (RA). There was assigned anti-CCP serum level, disease activity score by the formula for DAS28(3)-CRP and assessed radiological changes degree after Steinbrocker score. In 132 patient (62.559%) the serum anti-CCP concentration was positive for RA. Specificity of the test was 100% and sensitivity 65% (Z = 0.731, p = 0.465). There is a medium intensity correlation between variables representing anti-CCP and Steinbrocker score. Pearson's coefficient was 0.479 and Spearman's rank correlation coefficient was 0.614, i.e. statistically significant (p = 0.000). There is no statistically significant correlation between variables representing anti-CCP and DAS28(3)-CRP Anti-CCP are good RA predictor and their concentration correlate with radiological damages degree.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove
Medicinski fakultet, Osijek

Citiraj ovu publikaciju

Glasnović, Marija; Bošnjak, Ivica; Včev, Aleksandar; Soldo, Ivan; Glasnović-Horvatić, Elizabeta; Soldo-Butković, Silva; Pavela, Jasna; Mićunović, Nikola
Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28) // Collegium antropologicum, 31 (2007), 1; 345-348 (međunarodna recenzija, članak, znanstveni)
Glasnović, M., Bošnjak, I., Včev, A., Soldo, I., Glasnović-Horvatić, E., Soldo-Butković, S., Pavela, J. & Mićunović, N. (2007) Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28). Collegium antropologicum, 31 (1), 345-348.
@article{article, year = {2007}, pages = {345-348}, keywords = {anti-citrullinated antibodies, rheumatoid arthritis, disease activity score, radiological damages}, journal = {Collegium antropologicum}, volume = {31}, number = {1}, issn = {0350-6134}, title = {Anti-citrullinated antibodies, radiological joint damages and their correlations with disease activity score (DAS28)}, keyword = {anti-citrullinated antibodies, rheumatoid arthritis, disease activity score, radiological damages} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Social Science Citation Index (SSCI)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE